Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 11/20 | 0.43 |
| ▸ | FABP3 | P05413 | 2/20 | 0.43 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8375966 | 0.89 | FABP4 (0.41) | FABP4FABP3PLA2G2AHTR6 | |
| SCHEMBL8374848 | 0.89 | FABP4 (0.41) | FABP4FABP3PLA2G2AHTR6 | |
| SCHEMBL6697582 | 0.87 | PLA2G2A (0.44) | FABP4FABP3PLA2G2AHTR6 | |
| SCHEMBL6129678 | 0.87 | FABP4 (0.43) | FABP4FABP3PLA2G2AHTR6 | |
| SCHEMBL27844976 | 0.85 | FABP4 (0.39) | FABP4FABP3PLA2G2AHTR6 | |
| SCHEMBL818322 | 0.85 | PLA2G2A (0.47) | PLA2G2A | |
| SCHEMBL29862757 | 0.85 | PLA2G2A (0.47) | PLA2G2A | |
| SCHEMBL6129679 | 0.84 | FABP4 (0.38) | FABP4FABP3PLA2G2AHTR6 | |
| SCHEMBL6691719 | 0.83 | PLA2G2A (0.49) | FABP4FABP3PLA2G2AHTR6 | |
| SCHEMBL6693186 | 0.82 | PLA2G2A (0.49) | PLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0952149-A2 | Substituted carbazoles, process for their preparation and their use as sPLA2 inhibitiors | ELI LILLY AND COMPANY (US) | 1999-10-27 | — | — | EP | claimed |