Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | MGAM | O43451 | 1/20 | 0.40 |
| ▸ | SI | P14410 | 1/20 | 0.40 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | PPOX | P50336 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | PDE2A | O00408 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.37 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14044153 | 0.85 | P2RX3 (0.44) | GAANPC1TAAR1MAPTRAB9A | |
| SCHEMBL13683167 | 0.80 | P2RX3 (0.43) | GAANPC1MGAMSIMGAM2 | |
| SCHEMBL11467850 | 0.79 | PDE2A (0.43) | LMNAKDM4EPDE2AALDH1A1 | |
| SCHEMBL27263256 | 0.78 | GAA (0.42) | GAANPC1TAAR1MAPTRAB9A | |
| SCHEMBL20794220 | 0.76 | GAA (0.43) | GAAMGAMSIMGAM2MAPT | |
| SCHEMBL16200302 | 0.76 | GAA (0.41) | GAANPC1MGAMSIMGAM2 | |
| SCHEMBL8188425 | 0.76 | NPC1 (0.40) | GAANPC1TAAR1MAPTRAB9A | |
| SCHEMBL29328271 | 0.74 | P2RX3 (0.44) | GAANPC1MGAMSIMGAM2 | |
| SCHEMBL8186047 | 0.73 | NPC1 (0.40) | GAANPC1TAAR1MAPTRAB9A | |
| SCHEMBL23214729 | 0.73 | GAA (0.44) | GAANPC1MGAMSIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0772579-B1 | BENZOYL DERIVATIVES AND SYNTHESIS THEREOF | MONSANTO CO (US) | 1999-03-10 | — | — | EP | disclosed |
| EP-0772579-A1 | BENZOYL DERIVATIVES AND SYNTHESIS THEREOF | MONSANTO COMPANY (US) | 1997-05-14 | — | — | EP | disclosed |
| US-5600008-A | ACYLATION | MONSANTO COMPANY (US) | 1997-02-04 | — | — | US | disclosed |
| US-5600016-A | REACTING WITH A 1,1-DIHALOALKYLALKYL ETHER IN THE PRESENCE OF AN ACID ALKYLATION CATALYST | MONSANTO COMPANY (US) | 1997-02-04 | — | — | US | disclosed |
| WO-1996002485-A1 | BENZOYL DERIVATIVES AND SYNTHESIS THEREOF | MONSANTO COMPANY (US) | 1996-02-01 | — | — | WO | disclosed |