Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | PDE4A | P27815 | 1/20 | 0.54 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.54 |
| ▸ | TTPA | P49638 | 3/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.51 |
| ▸ | PSEN1 | P49768 | 11/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14168733 | 0.86 | MEN1 (0.64) | MEN1KMT2APDE4APDE3ATTPA | |
| SCHEMBL7331108 | 0.84 | MEN1 (0.55) | MEN1KMT2APDE4APDE3ATTPA | |
| SCHEMBL8614843 | 0.84 | MEN1 (0.50) | MEN1KMT2APDE4APDE3ATTPA | |
| SCHEMBL5268436 | 0.82 | MEN1 (0.56) | MEN1KMT2APDE4APDE3ATTPA | |
| SCHEMBL8376060 | 0.81 | MEN1 (0.64) | MEN1KMT2APDE4APDE3ATTPA | |
| SCHEMBL8380309 | 0.80 | TTPA (0.69) | MEN1KMT2APDE4APDE3ATTPA | |
| SCHEMBL10535364 | 0.80 | MEN1 (0.54) | MEN1KMT2APDE4APDE3ATTPA | |
| SCHEMBL10724905 | 0.80 | MEN1 (0.62) | MEN1KMT2APDE4APDE3ATTPA | |
| SCHEMBL8843005 | 0.80 | MEN1 (0.62) | MEN1KMT2APDE4APDE3ATTPA | |
| SCHEMBL9656784 | 0.80 | MEN1 (0.62) | MEN1KMT2APDE4APDE3ATTPA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0718295-B1 | Lactones with antioxidising and hypolipidaemic activity useful in the therapy of the atherosclerosis | ALFA WASSERMANN SPA (IT) | 1998-04-22 | — | — | EP | disclosed |
| US-5608084-A | AND VASCULAR PATHOLOGIES; MULTISTEP PREPARATION BY REACTING A HYDROQUINONE WITH ALKYL VINYL KETONE, ESTERIFYING HYDROXY 3,4-DIHYDRO-2H-1-BENZOPYRAN, DEMETHYLATING ETHER, REACTING WITH ALKYL 5-BROMOPENTANOATE, HYDROLYZING, TWO MORE STEPS | ALFA WASSERMANN S.P.A. (IT) | 1997-03-04 | — | — | US | disclosed |
| EP-0718295-A1 | Lactones with antioxidising and hypolipidaemic activity useful in the therapy of the atherosclerosis | ALFA WASSERMANN S.p.A. (IT) | 1996-06-26 | — | — | EP | disclosed |