SCHEMBL8376142

SCHEMBL8376142

ClCC[P+](c1ccccc1)(c1ccccc1)c1ccccc1.ClCC[P+](c1ccccc1)(c1ccccc1)c1ccccc1.F[Mn-](F)(F)F.F[Mn-](F)(F)F

nearest known ligand 0.58

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 1/20 0.58
ALDH1A1 P00352 1/20 0.45
CYP1A2 P05177 1/20 0.45
CYP2D6 P10635 1/20 0.45
TSHR P16473 1/20 0.45
CYP2C19 P33261 1/20 0.45
CHRNA7 P36544 8/20 0.34
SNCA P37840 2/20 0.33
TRAP1 Q12931 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL2448860 0.89 HIF1A (0.67) HIF1AALDH1A1CYP1A2CYP2D6TSHR
SCHEMBL8374692 0.87 HIF1A (0.58) HIF1AALDH1A1CYP1A2CYP2D6TSHR
SCHEMBL8375270 0.87 HIF1A (0.58) HIF1AALDH1A1CYP1A2CYP2D6TSHR
SCHEMBL8373298 0.87 HIF1A (0.58) HIF1AALDH1A1CYP1A2CYP2D6TSHR
SCHEMBL8604643 0.87 HIF1A (0.58) HIF1AALDH1A1CYP1A2CYP2D6TSHR
SCHEMBL8372333 0.83 HIF1A (0.58) HIF1AALDH1A1CYP1A2CYP2D6TSHR
SCHEMBL8374635 0.77 HIF1A (0.62) HIF1AALDH1A1CYP1A2CYP2D6TSHR
Acetic Acid SCHEMBL11664326 0.76 ALDH1A1 (0.53) HIF1AALDH1A1CYP1A2CYP2D6TSHR
SCHEMBL8376146 0.76 HIF1A (0.45) HIF1AALDH1A1CYP1A2CYP2D6TSHR
SCHEMBL31447346 0.75 HIF1A (1.00) HIF1AALDH1A1CYP1A2CYP2D6TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102382258-A Conjugated diene-based polymer, conjugated diene-based polymer composition, and process for producing conjugated diene-based polymer SUMITOMO CHEMICAL CO 2012-03-21 CN disclosed
US-5986042-A Cross-linked polymer MITSUI CHEMICALS, INC. (JP) 1999-11-16 US disclosed
CN-1031942-C Steroids containing spiro ring, process and intermediates for their prepn., their use as pharmaceutical compositions containing them ROUSSEL UCLAF (FR) 1996-06-05 CN disclosed
EP-0262188-B1 STEROIDS COMPRISING A SPIRANIC CYCLE IN POSITION 17, PREPARATION PROCESS AND UTILIZATION THEREOF ROUSSEL-UCLAF (FR) 1990-11-14 EP disclosed
CN-1034207-A New medicinal steroidal and preparation method thereof and intermediate, and the medicinal compositions that contains these steroidals ROUSSEL UCLAF (FR) 1989-07-26 CN disclosed
EP-0262188-A1 STEROIDS COMPRISING A SPIRANIC CYCLE IN POSITION 17, PREPARATION PROCESS AND UTILIZATION THEREOF. ROUSSEL UCLAF (FR) 1988-04-06 EP disclosed
WO-1987005908-A1 STEROIDS COMPRISING A SPIRANIC CYCLE IN POSITION 17, PREPARATION PROCESS AND UTILIZATION THEREOF ROUSSEL-UCLAF (FR) 1987-10-08 WO disclosed