Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C1S | P09871 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 3/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8372860 | 0.91 | NR1I2 (0.41) | C1SBRD4NPC1RAB9ACREBBP | |
| SCHEMBL30013328 | 0.78 | SMN1; SMN2 (0.56) | NPC1RAB9ALMNASMN1; SMN2MAPT | |
| SCHEMBL2357255 | 0.78 | SMN1; SMN2 (0.56) | NPC1RAB9ALMNASMN1; SMN2MAPT | |
| SCHEMBL112610 | 0.76 | DGAT1 (0.40) | BRD4NPC1RAB9ACREBBPLMNA | |
| SCHEMBL22900564 | 0.76 | MAPT (0.41) | BRD4NPC1RAB9ACREBBPLMNA | |
| SCHEMBL23242636 | 0.75 | MTNR1A (0.36) | BRD4NPC1RAB9ACREBBPLMNA | |
| SCHEMBL29224162 | 0.75 | BRD4 (0.38) | BRD4NPC1RAB9ACREBBPLMNA | |
| SCHEMBL22524619 | 0.74 | BRD4 (0.36) | BRD4NPC1RAB9ACREBBPLMNA | |
| SCHEMBL30040753 | 0.74 | BRD4 (0.39) | BRD4CREBBPLMNASMN1; SMN2HTT | |
| SCHEMBL6041792 | 0.74 | BRD4 (0.36) | BRD4NPC1CREBBPLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0625511-B1 | Heterocyclic compounds and their use in pharmaceutical | ZENECA LTD (GB) | 1999-02-17 | — | — | EP | disclosed |
| US-5504089-A | TREATING URINARY INCONTINENCE | ZENECA LIMITED (GB) | 1996-04-02 | — | — | US | disclosed |
| EP-0625511-A1 | Heterocyclic compounds and their use in pharmaceutical | ZENECA LIMITED (GB) | 1994-11-23 | — | — | EP | disclosed |