Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 17/20 | 1.00 |
| ▸ | PTGS1 | P23219 | 12/20 | 1.00 |
| ▸ | CA1 | P00915 | 3/20 | 0.44 |
| ▸ | CA2 | P00918 | 3/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8376350 | 0.89 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL7505993 | 0.81 | PTGS2 (0.86) | PTGS2PTGS1CA1CA2CA12 | |
| SCHEMBL7504621 | 0.81 | PTGS2 (0.76) | PTGS2PTGS1CA1CA2CA4 | |
| SCHEMBL8552519 | 0.81 | PTGS2 (0.76) | PTGS2PTGS1CA1CA2CA4 | |
| SCHEMBL8377543 | 0.80 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL7500833 | 0.79 | PTGS2 (0.65) | PTGS2PTGS1CA1CA2CA4 | |
| SCHEMBL8380735 | 0.77 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL213986 | 0.77 | PTGS2 (0.78) | PTGS2PTGS1CA1CA2CA4 | |
| SCHEMBL8551037 | 0.77 | PTGS2 (0.78) | PTGS2PTGS1CA1CA2CA4 | |
| SCHEMBL7799127 | 0.76 | PTGS2 (0.76) | PTGS2PTGS1CA1CA2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0826676-A1 | OXAZOLE DERIVATIVES AND USE THEREOF | Japan Tobacco Inc. (JP) | 1998-03-04 | — | — | EP | claimed |
| US-6002014-A | SELECTIVELY INHIBITING THE ACTION OF COX-2; TREATING INFLAMMATION | JAPAN TOBACCO, INC. (JP) | 1999-12-14 | — | — | US | disclosed |
| US-5945539-A | ENZYME INHIBITOR | JAPAN TOBACCO, INC. (JP) | 1999-08-31 | — | — | US | disclosed |
| EP-0826676-A1 | OXAZOLE DERIVATIVES AND USE THEREOF | Japan Tobacco Inc. (JP) | 1998-03-04 | — | — | EP | disclosed |