Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 11/20 | 0.95 |
| ▸ | CA9 | Q16790 | 10/20 | 0.95 |
| ▸ | CA12 | O43570 | 9/20 | 0.95 |
| ▸ | CA1 | P00915 | 8/20 | 0.95 |
| ▸ | CA7 | P43166 | 4/20 | 0.95 |
| ▸ | CA6 | P23280 | 3/20 | 0.95 |
| ▸ | CA5A | P35218 | 3/20 | 0.95 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.95 |
| ▸ | CA3 | P07451 | 2/20 | 0.95 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.62 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.60 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | CA4 | P22748 | 3/20 | 0.58 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.56 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | AGO2 | Q9UKV8 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| P-Toluenesulfonamide SCHEMBL1331323 | 0.97 | CA2 (1.00) | CA2CA9CA12CA1CA7 | |
| P-Toluenesulfonamide SCHEMBL31527821 | 0.97 | CA2 (1.00) | CA2CA9CA12CA1CA7 | |
| P-Toluenesulfonamide SCHEMBL7370 | 0.97 | CA2 (1.00) | CA2CA9CA12CA1CA7 | |
| P-Toluenesulfonamide SCHEMBL5492056 | 0.95 | CA2 (0.95) | CA2CA9CA12CA1CA7 | |
| P-Toluenesulfonamide SCHEMBL8376382 | 0.95 | CA2 (0.95) | CA2CA9CA12CA1CA7 | |
| P-Toluenesulfonamide SCHEMBL15401330 | 0.95 | CA2 (0.95) | CA2CA9CA12CA1CA7 | |
| P-Toluenesulfonamide SCHEMBL8070437 | 0.95 | CA2 (0.95) | CA2CA9CA12CA1CA7 | |
| P-Toluenesulfonamide SCHEMBL391243 | 0.95 | CA2 (0.95) | CA2CA9CA12CA1CA7 | |
| P-Toluenesulfonamide SCHEMBL9377640 | 0.95 | CA2 (0.95) | CA2CA9CA12CA1CA7 | |
| P-Toluenesulfonamide SCHEMBL357964 | 0.95 | CA2 (0.95) | CA2CA9CA12CA1CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5869472-A | Synthesis of 1α-hydroxy vitamin D | BONE CARE INTERNATIONAL, INC. (US) | 1999-02-09 | — | — | US | claimed |
| EP-0865427-A1 | SYNTHESIS OF 1ALPHA-HYDROXY VITAMIN D | BONE CARE INTERNATIONAL, INC. (US) | 1998-09-23 | — | — | EP | claimed |
| WO-1996002501-A1 | SYNTHESIS OF 1α-HYDROXY VITAMIN D | LUNAR CORPORATION (US) | 1996-02-01 | — | — | WO | claimed |
| US-5869472-A | Synthesis of 1α-hydroxy vitamin D | BONE CARE INTERNATIONAL, INC. (US) | 1999-02-09 | — | — | US | disclosed |
| EP-0865427-A1 | SYNTHESIS OF 1ALPHA-HYDROXY VITAMIN D | BONE CARE INTERNATIONAL, INC. (US) | 1998-09-23 | — | — | EP | disclosed |
| WO-1996002501-A1 | SYNTHESIS OF 1α-HYDROXY VITAMIN D | LUNAR CORPORATION (US) | 1996-02-01 | — | — | WO | disclosed |