Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.44 |
| ▸ | CA12 | O43570 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 3/20 | 0.33 |
| ▸ | CA1 | P00915 | 3/20 | 0.33 |
| ▸ | CA2 | P00918 | 3/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | PTPRB | P23467 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8376394 | 0.77 | CA14 (0.43) | CA14CA12SMN1; SMN2CA9CA1 | |
| SCHEMBL2651768 | 0.77 | CA14 (0.48) | CA14CA12SMN1; SMN2CA9CA1 | |
| SCHEMBL28010224 | 0.74 | CA14 (0.44) | CA14CA12SMN1; SMN2CA9CA1 | |
| SCHEMBL9125708 | 0.73 | CA12 (0.47) | CA14CA12SMN1; SMN2CA9CA1 | |
| SCHEMBL3647648 | 0.72 | CA1 (0.39) | CA14CA12SMN1; SMN2CA9CA1 | |
| SCHEMBL2864267 | 0.71 | SMN1; SMN2 (0.48) | CA14CA12SMN1; SMN2CA1CA2 | |
| SCHEMBL4616218 | 0.70 | SMN1; SMN2 (0.71) | CA14CA12SMN1; SMN2CA1CA2 | |
| SCHEMBL22268721 | 0.69 | CASR (0.37) | CA14CA12SMN1; SMN2CA9CA1 | |
| SCHEMBL6557447 | 0.69 | CA4 (0.30) | — | |
| SCHEMBL27949562 | 0.69 | CA14 (0.41) | CA14CA12SMN1; SMN2CA9CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5932567-A | Thrombin inhibitors | BASF AKTIENGESELLSCHAFT (DE) | 1999-08-03 | — | — | US | disclosed |
| EP-0809651-A1 | THROMBIN INHIBITORS | BASF AKTIENGESELLSCHAFT (DE) | 1997-12-03 | — | — | EP | disclosed |
| WO-1996024609-A1 | THROMBIN INHIBITORS | BASF AKTIENGESELLSCHAFT (DE) | 1996-08-15 | — | — | WO | disclosed |