Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.43 |
| ▸ | CA12 | O43570 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 3/20 | 0.33 |
| ▸ | CA1 | P00915 | 3/20 | 0.33 |
| ▸ | CA2 | P00918 | 3/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8376397 | 0.77 | CA14 (0.44) | CA14CA12SMN1; SMN2CA9CA1 | |
| SCHEMBL2651768 | 0.75 | CA14 (0.48) | CA14CA12SMN1; SMN2CA9CA1 | |
| SCHEMBL9125708 | 0.71 | CA12 (0.47) | CA14CA12SMN1; SMN2CA9CA1 | |
| SCHEMBL3647648 | 0.70 | CA1 (0.39) | CA14CA12SMN1; SMN2CA9CA1 | |
| SCHEMBL31572036 | 0.69 | LMNA (0.32) | — | |
| SCHEMBL270012 | 0.69 | — | — | |
| SCHEMBL453120 | 0.69 | SMN1; SMN2 (0.50) | CA14CA12SMN1; SMN2CA1CA2 | |
| SCHEMBL1332029 | 0.69 | — | — | |
| SCHEMBL2864267 | 0.69 | SMN1; SMN2 (0.48) | CA14CA12SMN1; SMN2CA1CA2 | |
| SCHEMBL15902979 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5932567-A | Thrombin inhibitors | BASF AKTIENGESELLSCHAFT (DE) | 1999-08-03 | — | — | US | disclosed |