SCHEMBL8376753

SCHEMBL8376753

C=CC[Si](CC=C)(CC=C)CCCN(CC)CC

nearest known ligand 0.41

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.41
POLB P06746 1/20 0.41
KMT2A Q03164 1/20 0.41
HRH4 Q9H3N8 2/20 0.33
HRH3 Q9Y5N1 2/20 0.33
ALDH1A1 P00352 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2508186 0.83 MEN1 (0.38) MEN1POLBKMT2AALDH1A1
SCHEMBL19863304 0.77 TSHR (0.43) ALDH1A1
SCHEMBL2505334 0.75 MEN1 (0.32) MEN1POLBKMT2A
SCHEMBL4301149 0.75 TSHR (0.44) ALDH1A1
SCHEMBL2502556 0.74 MEN1 (0.41) MEN1POLBKMT2A
SCHEMBL2501823 0.74 MEN1 (0.36) MEN1POLBKMT2AHRH4HRH3
SCHEMBL22129498 0.74 ALDH1A1 (0.38) MEN1POLBKMT2AHRH4HRH3
SCHEMBL8047254 0.73 TSHR (0.48) MEN1KMT2AALDH1A1
SCHEMBL6270384 0.73 TSHR (0.48) MEN1KMT2AALDH1A1
SCHEMBL3900120 0.72 TSHR (0.43) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5968652-A Silane coated particle 3M INNOVATIVE PROPERTIES COMPANY (US) 1999-10-19 US disclosed
US-5876595-A OLEFINIC SILANES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1999-03-02 US disclosed
US-5667674-A POLYCARBOSILANE MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-09-16 US disclosed