Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | FDPS | P14324 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8677374 | 0.85 | MAPT (0.40) | TP53FDPSTSHRTNFRSF1AL3MBTL1 | |
| SCHEMBL8636164 | 0.81 | LMNA (0.39) | FDPSL3MBTL1LMNAMAPTALDH1A1 | |
| SCHEMBL875062 | 0.76 | KMT2A (0.48) | TSHRPDE4DL3MBTL1LMNAMAPT | |
| SCHEMBL22144400 | 0.72 | MEN1 (0.49) | TSHRL3MBTL1LMNAMAPTTDP1 | |
| SCHEMBL22283800 | 0.72 | MEN1 (0.49) | TSHRL3MBTL1LMNAMAPTTDP1 | |
| SCHEMBL10640237 | 0.72 | MEN1 (0.47) | L3MBTL1LMNA | |
| SCHEMBL10853633 | 0.72 | MEN1 (0.47) | L3MBTL1LMNA | |
| SCHEMBL490607 | 0.69 | AOC3 (0.46) | TSHRMAPK1L3MBTL1LMNAMAPT | |
| SCHEMBL8677379 | 0.69 | TNFRSF1A (0.40) | TP53FDPSTSHRMAPK1TNFRSF1A | |
| SCHEMBL8377259 | 0.68 | SMN1; SMN2 (0.47) | FDPSTSHRMAPK1TNFRSF1AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5883248-A | QUATERNARY AMMONIUM INTERMEDIATES | ROUSSEL UCLAF (FR) | 1999-03-16 | — | — | US | disclosed |
| US-5728828-A | A 3-(3-CHLORO- OR IODOPROP-1-EN-1-YL),7-(2-AMINOTHIAZOL-4-YL) ((CARBOXY)(PHENYL)METHOXYIMINO)ACETAMIDO-3-CEPHEM; GRAMNEGATIVE AND -POSITIVE BACTERIA, ESP. ANTIBIOTIC-RESISTANCE STAPHYLOCOCCUS | ROUSSEL UCLAF (FR) | 1998-03-17 | — | — | US | disclosed |