Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 3/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 7/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 7/20 | 0.45 |
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | MMP3 | P08254 | 1/20 | 0.45 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.45 |
| ▸ | NMUR2 | Q9GZQ4 | 2/20 | 0.43 |
| ▸ | NMUR1 | Q9HB89 | 2/20 | 0.43 |
| ▸ | GRB2 | P62993 | 1/20 | 0.42 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.42 |
| ▸ | XIAP | P98170 | 2/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8950750 | 0.96 | ACE (0.43) | ACEOPRM1OPRK1MMP1MMP3 | |
| SCHEMBL21068023 | 0.93 | OPRM1 (0.44) | ACEOPRM1OPRK1MMP1MMP3 | |
| SCHEMBL6924797 | 0.88 | F2 (0.48) | ACEOPRM1OPRK1EPHA2FKBP1A | |
| SCHEMBL7270558 | 0.85 | ACE (0.47) | ACEOPRM1OPRK1MMP1MMP3 | |
| SCHEMBL8837276 | 0.85 | F2 (0.49) | ACEOPRM1OPRK1EPHA2NMUR2 | |
| SCHEMBL29391363 | 0.85 | GRB2 (0.55) | OPRM1OPRK1EPHA2NMUR2NMUR1 | |
| SCHEMBL30416412 | 0.84 | GRB2 (0.47) | OPRM1OPRK1EPHA2NMUR2NMUR1 | |
| SCHEMBL6850160 | 0.83 | F2 (0.57) | OPRM1OPRK1F2 | |
| SCHEMBL6497247 | 0.83 | F2 (0.57) | OPRM1OPRK1F2 | |
| SCHEMBL2119635 | 0.83 | F2 (0.57) | OPRM1OPRK1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0664786-B1 | ARGININE KETO-AMIDE ENZYME INHIBITORS | CORVAS INT INC (US) | 1999-03-24 | — | — | EP | disclosed |