Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 5/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
| ▸ | AKT2 | P31751 | 1/20 | 0.36 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.36 |
| ▸ | HRH2 | P25021 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8377726 | 1.00 | ITGB3 (0.47) | ITGB3ITGA2BPTGS2OPRD1F2 | |
| SCHEMBL8643771 | 0.91 | ITGB3 (0.45) | ITGB3ITGA2BPTGS2OPRD1F2 | |
| SCHEMBL8382697 | 0.84 | ITGB3 (0.49) | ITGB3ITGA2BPTGS2 | |
| SCHEMBL8382690 | 0.84 | ITGB3 (0.49) | ITGB3ITGA2BPTGS2 | |
| SCHEMBL8383179 | 0.83 | ITGB3 (0.48) | ITGB3ITGA2BKMT2A | |
| SCHEMBL8383182 | 0.83 | ITGB3 (0.48) | ITGB3ITGA2BKMT2A | |
| SCHEMBL2009677 | 0.80 | ITGB3 (0.67) | ITGB3ITGA2BOPRD1HRH2HRH1 | |
| SCHEMBL8646548 | 0.77 | ITGB3 (0.46) | ITGB3ITGA2B | |
| SCHEMBL3856287 | 0.73 | PTGS2 (0.65) | ITGB3ITGA2BPTGS2HSD17B10KDM4E | |
| SCHEMBL8646550 | 0.72 | ITGB3 (0.39) | ITGB3ITGA2BPTGS2HSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5973188-A | Acetic acid derivatives | HOFFMANN-LA ROCHE INC. (US) | 1999-10-26 | — | — | US | disclosed |