Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.65 |
| ▸ | ATM | Q13315 | 1/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30452117 | 0.93 | L3MBTL1 (0.78) | TDP1ATML3MBTL1ALDH1A1MEN1 | |
| SCHEMBL4667551 | 0.93 | L3MBTL1 (0.78) | TDP1ATML3MBTL1ALDH1A1MEN1 | |
| SCHEMBL279656 | 0.92 | ALDH1A1 (0.59) | TDP1ATML3MBTL1ALDH1A1MEN1 | |
| Ethylene Glycol SCHEMBL9374043 | 0.86 | L3MBTL1 (0.67) | TDP1ATML3MBTL1ALDH1A1MEN1 | |
| SCHEMBL4958273 | 0.85 | ALDH1A1 (0.53) | TDP1ATML3MBTL1ALDH1A1MEN1 | |
| SCHEMBL25142152 | 0.83 | L3MBTL1 (0.52) | TDP1ATML3MBTL1ALDH1A1KMT2A | |
| Sulfuric Acid SCHEMBL28400618 | 0.83 | ALDH1A1 (0.58) | TDP1ATML3MBTL1ALDH1A1MEN1 | |
| SCHEMBL29902348 | 0.83 | CA12 (0.58) | TDP1ATML3MBTL1ALDH1A1MEN1 | |
| SCHEMBL246827 | 0.83 | CA12 (0.58) | TDP1ATML3MBTL1ALDH1A1MEN1 | |
| SCHEMBL18084558 | 0.82 | CDC25A (0.54) | TDP1ATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5958376-A | Iodinated X-ray contrast media | NYCOMED IMAGING AS (NO) | 1999-09-28 | — | — | US | disclosed |
| US-5958375-A | Urea-linked, iodinated bis phenyl compounds for X-ray contrast media | NYCOMED IMAGING AS (NO) | 1999-09-28 | — | — | US | disclosed |
| EP-0782565-B1 | IODINATED X-RAY-CONTRAST MEDIA | NYCOMED IMAGING AS (NO) | 1999-04-07 | — | — | EP | disclosed |
| CN-1164225-A | Iodinated X-ray-contrast media | NYCOMED IMAGING AS (NO) | 1997-11-05 | — | — | CN | disclosed |
| EP-0782565-A1 | IODINATED X-RAY-CONTRAST MEDIA | NYCOMED IMAGING AS (NO) | 1997-07-09 | — | — | EP | disclosed |
| WO-1996009285-A1 | IODINATED X-RAY-CONTRAST MEDIA | NYCOMED IMAGING AS (NO) | 1996-03-28 | — | — | WO | disclosed |