Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | MAP2K1 | Q02750 | 6/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.32 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.32 |
| ▸ | IARS2 | Q9NSE4 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8375505 | 0.92 | LMNA (0.54) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL8383119 | 0.91 | LMNA (0.48) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL8081022 | 0.91 | LMNA (0.51) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL4923455 | 0.88 | LMNA (0.51) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL9513442 | 0.86 | LMNA (0.55) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL619959 | 0.86 | LMNA (0.58) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL8374113 | 0.86 | LMNA (0.52) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL8373468 | 0.86 | LMNA (0.51) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL8377190 | 0.86 | LMNA (0.49) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL28469692 | 0.85 | LMNA (0.54) | LMNACYP2C19HIF1AEGFRSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5958376-A | Iodinated X-ray contrast media | NYCOMED IMAGING AS (NO) | 1999-09-28 | — | — | US | disclosed |
| US-5958375-A | Urea-linked, iodinated bis phenyl compounds for X-ray contrast media | NYCOMED IMAGING AS (NO) | 1999-09-28 | — | — | US | disclosed |
| EP-0782565-A1 | IODINATED X-RAY-CONTRAST MEDIA | NYCOMED IMAGING AS (NO) | 1997-07-09 | — | — | EP | disclosed |
| WO-1996009285-A1 | IODINATED X-RAY-CONTRAST MEDIA | NYCOMED IMAGING AS (NO) | 1996-03-28 | — | — | WO | disclosed |