Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | MAP2K1 | Q02750 | 6/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.32 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.32 |
| ▸ | IARS2 | Q9NSE4 | 1/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8375505 | 0.93 | LMNA (0.54) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL8379792 | 0.90 | LMNA (0.51) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL622239 | 0.87 | LMNA (0.54) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL8377995 | 0.86 | LMNA (0.47) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL8373468 | 0.85 | LMNA (0.51) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL8374113 | 0.85 | LMNA (0.52) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL9563100 | 0.84 | LMNA (0.52) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL621824 | 0.84 | LMNA (0.52) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL8517921 | 0.84 | LMNA (0.46) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL8375497 | 0.83 | LMNA (0.56) | LMNACYP2C19HIF1ACHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5958376-A | Iodinated X-ray contrast media | NYCOMED IMAGING AS (NO) | 1999-09-28 | — | — | US | disclosed |
| US-5958375-A | Urea-linked, iodinated bis phenyl compounds for X-ray contrast media | NYCOMED IMAGING AS (NO) | 1999-09-28 | — | — | US | disclosed |