⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5167642 | 0.84 | — | — | |
| SCHEMBL9241 | 0.80 | — | — | |
| SCHEMBL7927829 | 0.80 | KDM5A (0.43) | — | |
| SCHEMBL147823 | 0.80 | — | — | |
| SCHEMBL9074 | 0.78 | SIGMAR1 (0.40) | — | |
| SCHEMBL7931175 | 0.78 | CYP1A2 (0.41) | — | |
| SCHEMBL232247 | 0.76 | MEN1 (0.39) | — | |
| SCHEMBL15052708 | 0.76 | MEN1 (0.39) | — | |
| SCHEMBL6521475 | 0.76 | LMNA (0.31) | — | |
| SCHEMBL8989 | 0.76 | CA12 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3271 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230174483-A1 | INDIRUBIN DERIVATIVES, AND USES THEREOF | CITY OF HOPE (US) | 2023-06-08 | — | — | US | claimed |
| US-11548900-B2 | Oxazino-quinazoline and oxazino-quinoline type compound, preparation method and uses thereof | BEIJING SCITECH-MQ PHARMACEUTICALS LIMITED (CN) | 2023-01-10 | — | — | US | claimed |
| CN-114181217-A | Pyrazolo [1,5-a ] [1,3,5] triazine derivative and salt thereof and application of derivative and salt thereof in preparation of anti-cancer drugs | 陕西师范大学 | 2022-03-15 | — | — | CN | claimed |
| EP-3952995-A1 | BICYCLIC HETEROARYL DERIVATIVES AS ECTONUCLEOTIDE PYROPHOSPHATASE PHOSPHODIESTERASE 1 INHIBITORS | Riboscience LLC (US) | 2022-02-16 | — | — | EP | claimed |
| CN-114040915-A | Bicyclic heteroaryl derivatives as ectonucleotide pyrophosphatase phosphodiesterase 1 inhibitors | 里伯赛恩斯有限责任公司 | 2022-02-11 | — | — | CN | claimed |
| EP-3760633-B1 | OXAZINO-QUINAZOLINE AND OXAZINO-QUINAZOLINE TYPE COMPOUND, PREPARATION METHOD THEREFOR, AND USES THEREOF | BEIJING SCITECH MQ PHARMACEUTICALS LTD (CN) | 2021-12-15 | — | — | EP | claimed |
| CN-109748910-B | Quinazolinone compound, preparation method and medical application thereof | 徐州医科大学 | 2021-04-30 | — | — | CN | claimed |
| CN-110229171-B | Oxazinoquinazoline and oxazinoquinoline compound and preparation method and application thereof | 北京赛特明强医药科技有限公司 | 2021-03-12 | — | — | CN | claimed |
| US-20210040114-A1 | OXAZINO-QUINAZOLINE AND OXAZINO-QUINOLINE TYPE COMPOUND, PREPARATION METHOD AND USES THEREOF | ACCSALUS BIOSCIENCES LIMITED (VG) | 2021-02-11 | — | — | US | claimed |
| EP-3760633-A1 | OXAZINO-QUINAZOLINE AND OXAZINO-QUINAZOLINE TYPE COMPOUND, PREPARATION METHOD THEREFOR, AND USES THEREOF | Beijing Scitech-MQ Pharmaceuticals Limited (CN) | 2021-01-06 | — | — | EP | claimed |
| US-4588730-A | Pyrazolo[3,4,5-k1]acridine compositions and methods for their use as antimicrobials | WARNER-LAMBERT COMPANY (US) | 1986-05-13 | — | — | US | claimed |
| US-4555572-A | Pyrazolo[3,4,5-kl]acridine compositions and methods for their production and use | WARNER-LAMBERT COMPANY (US) | 1985-11-26 | — | — | US | claimed |
| EP-0023559-B1 | 2-(PERHYDRO-1,4-DIAZINO)-PYRIMIDO(5,4-D)PYRIMIDINES, THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | Dr. Karl Thomae GmbH (DE) | 1984-09-19 | — | — | EP | claimed |
| EP-0058779-B1 | CARBOXAMIDES, THEIR PREPARATION AND THEIR USE AS MEDICINES | Dr. Karl Thomae GmbH (DE) | 1984-09-19 | — | — | EP | claimed |
| US-4442119-A | Cyclopropyl analogs as estrogenic and anti-fertility agents | THE BOARD OF REGENTS FOR THE UNIVERSITY OF OKLAHOMA (US) | 1984-04-10 | — | — | US | claimed |
| US-4439438-A | ANTIDEPRESSANTS, INOTROPIC AGENTS | CAVAZZA CLAUDIO (IT) | 1984-03-27 | — | — | US | claimed |
| EP-0013144-B1 | SUBSTITUTED DIPHENYLAMINE DERIVATIVES, COMPOSITIONS AND HERBICIDAL USES THEREOF, AND PROCESSES FOR THEIR PREPARATION | ICI AUSTRALIA LIMITED (AU) | 1983-02-23 | — | — | EP | claimed |
| EP-0013144-A1 | Substituted diphenylamine derivatives, compositions and herbicidal uses thereof, and processes for their preparation | ICI AUSTRALIA LIMITED (AU) | 1980-07-09 | — | — | EP | claimed |
| US-3937712-A | MICROBIOCIDES | BOEHRINGER INGELHEIM GMBH (DT) | 1976-02-10 | — | — | US | claimed |
| US-3932643-A | INTERFERON INDUCERS | PFIZER INC. (US) | 1976-01-13 | — | — | US | claimed |