Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHUK | O15111 | 9/20 | 0.78 |
| ▸ | ICOSLG | O75144 | 8/20 | 0.78 |
| ▸ | ICOS | Q9Y6W8 | 8/20 | 0.78 |
| ▸ | IKBKB | O14920 | 2/20 | 0.78 |
| ▸ | MEN1 | O00255 | 1/20 | 0.78 |
| ▸ | PIM1 | P11309 | 1/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.78 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.78 |
| ▸ | IKBKG | Q9Y6K9 | 1/20 | 0.78 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.48 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.47 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.47 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29359984 | 0.88 | CHUK (1.00) | CHUKICOSLGICOSIKBKBMEN1 | |
| SCHEMBL1420453 | 0.88 | CHUK (1.00) | CHUKICOSLGICOSIKBKBMEN1 | |
| Hydrochloric Acid SCHEMBL12471533 | 0.87 | CHUK (0.98) | CHUKICOSLGICOSIKBKBMEN1 | |
| SCHEMBL14253037 | 0.80 | CHUK (1.00) | CHUKICOSLGICOSIKBKBMEN1 | |
| SCHEMBL14253079 | 0.77 | CHUK (0.67) | CHUKICOSLGICOSIKBKBMEN1 | |
| SCHEMBL13377038 | 0.77 | CHUK (1.00) | CHUKICOSLGICOSIKBKBMEN1 | |
| SCHEMBL13376959 | 0.76 | CHUK (0.89) | CHUKICOSLGICOSIKBKBMEN1 | |
| SCHEMBL2768947 | 0.75 | CHUK (0.78) | CHUKICOSLGICOSIKBKBMEN1 | |
| SCHEMBL2767580 | 0.74 | CHUK (0.74) | CHUKICOSLGICOSIKBKBMEN1 | |
| SCHEMBL14253078 | 0.73 | CHUK (0.83) | CHUKICOSLGICOSIKBKBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090297533-A1 | CONTROLLED RELEASE IMMUNOMODULATOR COMPOSITIONS AND METHODS FOR THE TREATMENT OF OTIC DISORDERS | OTONOMY, INC. (US) | 2009-12-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090297533-A1 | CONTROLLED RELEASE IMMUNOMODULATOR COMPOSITIONS AND METHODS FOR THE TREATMENT OF OTIC DISORDERS | OTC, CD74, TSLP | CHUK 2872/4885ICOSLG 51/4885ICOS 12/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.