Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.42 |
| ▸ | CETP | P11597 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11680871 | 1.00 | SIGMAR1 (0.48) | SIGMAR1KCNH2CHRM2HTR1AADRA2A | |
| SCHEMBL28123637 | 0.92 | KCNH2 (0.49) | SIGMAR1KCNH2CHRM2HTR1AADRA2A | |
| SCHEMBL1350580 | 0.81 | DNM1 (0.44) | SIGMAR1KCNH2TP53SMN1; SMN2 | |
| SCHEMBL7083095 | 0.81 | DNM1 (0.44) | SIGMAR1KCNH2TP53SMN1; SMN2 | |
| SCHEMBL10523481 | 0.81 | DNM1 (0.44) | SIGMAR1KCNH2TP53SMN1; SMN2 | |
| SCHEMBL20366114 | 0.80 | SIGMAR1 (0.52) | SIGMAR1ADRA1ASLC6A3HPGDSMN1; SMN2 | |
| SCHEMBL6817649 | 0.78 | SIGMAR1 (0.41) | SIGMAR1KCNH2CETPHPGD | |
| Butylbenzyl SCHEMBL16051 | 0.77 | SIGMAR1 (0.59) | SIGMAR1KCNH2CHRM2HTR1AADRA2A | |
| Butylbenzyl SCHEMBL22716183 | 0.77 | SIGMAR1 (0.59) | SIGMAR1KCNH2CHRM2HTR1AADRA2A | |
| Butylbenzyl SCHEMBL3229215 | 0.77 | SIGMAR1 (0.59) | SIGMAR1KCNH2CHRM2HTR1AADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-11246448-A | — | — | None | — | — | JP | disclosed |
| JP-H11246448-A | PRODUCTION OF FLUORINE-CONTAINING ACETYLENE COMPOUND | SAGAMI CHEM RES CENTER | 1999-09-14 | — | — | JP | disclosed |