Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | PLAU | P00749 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6639870 | 0.91 | KDM4E (0.50) | KDM4EHPGDHSD17B10RAB9ANPC1 | |
| SCHEMBL27929103 | 0.84 | KDM4E (0.46) | KDM4EHPGDHSD17B10RAB9ANPC1 | |
| SCHEMBL8374606 | 0.84 | ALDH1A1 (0.45) | KDM4ERAB9ANPC1SMN1; SMN2GAA | |
| Hydrochloric Acid SCHEMBL8374642 | 0.83 | ALDH1A1 (0.44) | KDM4ERAB9ANPC1SMN1; SMN2GAA | |
| SCHEMBL2485976 | 0.80 | NPC1 (0.58) | KDM4EHPGDRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL2043804 | 0.80 | CTSA (0.49) | SMN1; SMN2GAAALDH1A1ATM | |
| SCHEMBL4634043 | 0.79 | TDP1 (0.42) | KDM4EHPGDHSD17B10GAAALDH1A1 | |
| SCHEMBL31410892 | 0.79 | ALDH1A1 (0.42) | KDM4ERAB9ANPC1SMN1; SMN2GAA | |
| Carbamic Acid SCHEMBL28265554 | 0.79 | PLAU (0.53) | RAB9ANPC1SMN1; SMN2GAATP53 | |
| SCHEMBL8374641 | 0.77 | GAA (0.46) | KDM4ERAB9ANPC1SMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0900202-A1 | 3-ALKOXYPYRIDINE-2-CARBOXYLIC ACID AMIDE ESTERS, THEIR PREPARATION AND THEIR USE AS DRUGS | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-03-10 | — | — | EP | disclosed |
| WO-1997041103-A1 | 3-ALKOXYPYRIDINE-2-CARBOXYLIC ACID AMIDE ESTERS, THEIR PREPARATION AND THEIR USE AS DRUGS | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-11-06 | — | — | WO | disclosed |