Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.43 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.40 |
| ▸ | CTSA | P10619 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8809536 | 0.99 | GAA (0.45) | GAAPOLBSMN1; SMN2EGLN2FTO | |
| SCHEMBL8375973 | 0.89 | SSTR4 (0.42) | GAAPOLBSMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL8378285 | 0.84 | LMNA (0.38) | GAAPOLBSMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL8374350 | 0.83 | SMN1; SMN2 (0.39) | GAAPOLBSMN1; SMN2MAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL8374272 | 0.83 | LMNA (0.42) | GAASMN1; SMN2MAPTALDH1A1LMNA | |
| SCHEMBL8374349 | 0.82 | FAAH (0.40) | SMN1; SMN2MAPTALDH1A1LMNANPSR1 | |
| SCHEMBL4070937 | 0.81 | FTO (0.57) | GAAEGLN2FTOALDH1A1MAPK8 | |
| SCHEMBL8375877 | 0.80 | FAAH (0.46) | GAAPOLBSMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL8779171 | 0.80 | EGLN2 (0.46) | GAAEGLN2FTOMAPTALDH1A1 | |
| SCHEMBL8374372 | 0.80 | FAAH (0.43) | MAPTLMNAKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0900202-A1 | 3-ALKOXYPYRIDINE-2-CARBOXYLIC ACID AMIDE ESTERS, THEIR PREPARATION AND THEIR USE AS DRUGS | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-03-10 | — | — | EP | disclosed |
| WO-1997041103-A1 | 3-ALKOXYPYRIDINE-2-CARBOXYLIC ACID AMIDE ESTERS, THEIR PREPARATION AND THEIR USE AS DRUGS | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-11-06 | — | — | WO | disclosed |