Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | BAK1 | Q16611 | 1/20 | 0.31 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.30 |
| ▸ | LIPE | Q05469 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2529054 | 0.88 | F10 (0.44) | F10PDE4BCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL2529475 | 0.75 | F10 (0.44) | F10PDE4BCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL8378161 | 0.72 | PDE4B (0.52) | F10PDE4BLMNATSHRSMN1; SMN2 | |
| SCHEMBL2529572 | 0.71 | PDE4B (0.70) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL18015951 | 0.71 | PDE4B (0.57) | F10PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL13976101 | 0.69 | TSHR (0.49) | CYP1A2CYP2C9CYP2C19LMNATSHR | |
| SCHEMBL2529968 | 0.69 | UCHL1 (0.45) | PDE4BLMNAALDH1A1L3MBTL1PTGS2 | |
| SCHEMBL1313709 | 0.67 | TSHR (0.49) | F10CYP1A2CYP2C9CYP2C19LMNA | |
| SCHEMBL2532260 | 0.67 | F10 (0.49) | F10PDE4BCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL429160 | 0.65 | UCHL1 (0.40) | CYP1A2CYP2C9CYP2C19LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8039450-B2 | Boron-containing small molecules as anti-inflammatory agents | ANACOR PHARMACEUTICALS, INC. (US) | 2011-10-18 | — | — | US | disclosed |
| US-20090291917-A1 | Boron-Containing Small Molecules as Anti-Inflammatory Agents | ANACOR PHARMACEUTICALS, INC. (US) | 2009-11-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090291917-A1 | Boron-Containing Small Molecules as Anti-Inflammatory Agents | NFKBIA, LITAF, CD68 | F10 3796/4885PDE4B 776/4885CYP1A2 4597/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.