Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8375123 | 0.76 | — | — | |
| SCHEMBL9132263 | 0.76 | — | — | |
| SCHEMBL1090093 | 0.73 | SMN1; SMN2 (0.42) | CA12CA1CA2CA9MEN1 | |
| SCHEMBL15845026 | 0.70 | SMN1; SMN2 (0.40) | CA12CA1CA2CA9MEN1 | |
| SCHEMBL936005 | 0.68 | HTR4 (0.34) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL3363445 | 0.65 | ALDH1A1 (0.38) | SMN1; SMN2ALDH1A1GLARECQLHTT | |
| SCHEMBL3707562 | 0.65 | HTR4 (0.32) | — | |
| SCHEMBL1028962 | 0.64 | — | — | |
| SCHEMBL28648579 | 0.64 | CA12 (0.34) | CA12CA1CA2CA9SMN1; SMN2 | |
| SCHEMBL435747 | 0.64 | ALDH1A1 (0.38) | MEN1KMT2ASMN1; SMN2RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5869480-A | ALLEVIATING MEMORY DYSFUNCTION CHARACTERIZED BY CHOLINERGIC DEFICIT | HOECHST MARION ROUSSEL INC. (US) | 1999-02-09 | — | — | US | disclosed |
| US-5866565-A | ALZHEIMER'S DISORDERS | HOECHST MARION ROUSSEL INC. (US) | 1999-02-02 | — | — | US | disclosed |
| US-5821239-A | USEFUL FOR TREATING ALZHEIMER'S DISEASE CAUSED BY CHOLINERGIC DEFICIT | FROMMER LAWRENCE & HUAG LLP (US) | 1998-10-13 | — | — | US | disclosed |
| EP-0477903-B1 | Substituted-4-amino-3-pyridinols, a process for their preparation and their use as medicaments | HOECHST ROUSSEL PHARMA (US) | 1996-04-03 | — | — | EP | disclosed |
| EP-0477903-A2 | Substituted-4-amino-3-pyridinols, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1992-04-01 | — | — | EP | disclosed |
| US-4590074-A | SYMMETRICAL DERIVATIVES OF MITOMYCIN C-ANTITUMOR AGENTS | BRISTOL-MYERS COMPANY (US) | 1986-05-20 | — | — | US | disclosed |
| US-4579737-A | ANTITUMOR AGENTS | BRISTOL-MYERS COMPANY (US) | 1986-04-01 | — | — | US | disclosed |