SCHEMBL8378680

SCHEMBL8378680

CCCCCCCCCC(COP(=O)(N1CCOCC1)N1CCOCC1)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.43

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
FDPS P14324 1/20 0.32
CDC25A P30304 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8378684 0.85 FDPS (0.30) FDPS
SCHEMBL4923399 0.72
SCHEMBL8413717 0.69 MEN1 (0.46) MEN1KMT2A
SCHEMBL4923396 0.69 MEN1 (0.46) MEN1KMT2A
SCHEMBL8163873 0.68 TSHR (0.46) FDPS
SCHEMBL8378812 0.67 MEN1 (0.50) MEN1KMT2A
SCHEMBL28519708 0.66 FDPS (0.35) FDPS
Lithium Ion SCHEMBL14716399 0.65 CA2 (0.36) MEN1KMT2AFDPS
SCHEMBL20621508 0.65 FDPS (0.41) MEN1KMT2AFDPS
SCHEMBL28515200 0.64 FDPS (0.36) FDPS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0788347-B1 STABLE REVERSE AND MULTIPLE FLUOROCARBON EMULSIONS ALLIANCE PHARMA (US) 1999-08-11 EP disclosed
US-5904933-A Stable reverse and multiple fluorocarbon emulsions ALLIANCE PHARMACEUTICAL CORP. (US) 1999-05-18 US disclosed
EP-0788347-A1 STABLE REVERSE AND MULTIPLE FLUOROCARBON EMULSIONS ALLIANCE PHARMACEUTICAL CORPORATION (US) 1997-08-13 EP disclosed
WO-1995033447-A1 STABLE REVERSE AND MULTIPLE FLUOROCARBON EMULSIONS ALLIANCE PHARMACEUTICAL CORP. (GB) 1995-12-14 WO disclosed