Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 10/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 9/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | FLT3 | P36888 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | NOS3 | P29474 | 1/20 | 0.37 |
| ▸ | NOS1 | P29475 | 1/20 | 0.37 |
| ▸ | NOS2 | P35228 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.36 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | TIPARP | Q7Z3E1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL70661 | 0.98 | SLC6A4 (0.46) | SLC6A4SLC6A2SLC6A3KCNH2FLT3 | |
| SCHEMBL31322347 | 0.87 | SLC6A4 (0.44) | SLC6A4SLC6A2SLC6A3KCNH2ADRB1 | |
| SCHEMBL70403 | 0.79 | SLC6A2 (0.38) | SLC6A4SLC6A2SLC6A3IRAK4SLC18A3 | |
| Nitrogen SCHEMBL10785330 | 0.79 | HPGD (0.49) | — | |
| Hydrochloric Acid SCHEMBL70914 | 0.78 | HTR2C (0.38) | SLC6A4SLC6A2SLC6A3IRAK4SLC18A3 | |
| SCHEMBL1006288 | 0.77 | SIGMAR1 (0.45) | SLC6A4SLC6A2SLC6A3KCNH2FLT3 | |
| SCHEMBL83005 | 0.77 | HTR2C (0.53) | SLC6A4SLC6A2SLC6A3 | |
| Hydrochloric Acid SCHEMBL7331996 | 0.76 | SIGMAR1 (0.44) | SLC6A4SLC6A2SLC6A3KCNH2FLT3 | |
| Hydrochloric Acid SCHEMBL70546 | 0.76 | HTR2C (0.54) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL27432324 | 0.76 | SLC6A2 (0.36) | SLC6A4SLC6A2SLC6A3IRAK4SLC18A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129376-B2 | Piperidine derivatives as inhibitors of stearoyl-CoA desaturase | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2012-03-06 | — | — | US | disclosed |
| CN-102036558-A | Novel piperidine derivatives as stearoyl-CoA desaturase inhibitors | FOREST LAB HOLDINGS LTD | 2011-04-27 | — | — | CN | disclosed |
| US-20090239810-A1 | NOVEL PIPERAZINE DERIVATIVES AS INHIBITORS OF STEAROYL-CoA DESATURASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2009-09-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090239810-A1 | NOVEL PIPERAZINE DERIVATIVES AS INHIBITORS OF STEAROYL-CoA DESATURASE | SCD, SCD5, FADS2 | SLC6A4 4287/4885SLC6A2 4356/4885SLC6A3 4513/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.