SCHEMBL8379458

SCHEMBL8379458

C=CCCCCCCCCOc1ccc(C(=O)Cl)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.65
ALDH1A1 P00352 1/20 0.65
HTT P42858 1/20 0.54
GAA P10253 1/20 0.51
TP53 P04637 1/20 0.46
TSHR P16473 1/20 0.46
LSS P48449 6/20 0.46
PLA2G4B P0C869 1/20 0.45
PRMT1 Q99873 3/20 0.44
F2 P00734 2/20 0.44
ST14 Q9Y5Y6 2/20 0.44
PLAU P00749 1/20 0.44
PRMT5 O14744 1/20 0.44
SLC22A2 O15244 1/20 0.44
SLC22A1 O15245 1/20 0.44
TMPRSS2 O15393 1/20 0.44
PTP4A3 O75365 1/20 0.44
SLC22A3 O75751 1/20 0.44
F10 P00742 1/20 0.44
PLG P00747 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10261955 1.00 L3MBTL1 (0.65) L3MBTL1ALDH1A1HTTGAATP53
SCHEMBL8152256 0.98 L3MBTL1 (0.67) L3MBTL1ALDH1A1HTTGAATP53
SCHEMBL9145010 0.96 L3MBTL1 (0.60) L3MBTL1ALDH1A1HTTGAATP53
SCHEMBL5407527 0.94 L3MBTL1 (0.73) L3MBTL1ALDH1A1HTTGAATP53
SCHEMBL3229845 0.89 L3MBTL1 (0.61) L3MBTL1ALDH1A1HTTGAATSHR
SCHEMBL2370175 0.87 L3MBTL1 (0.69) L3MBTL1ALDH1A1HTTGAATP53
SCHEMBL9615211 0.87 GAA (0.66) L3MBTL1HTTGAATP53TSHR
SCHEMBL8379459 0.86 ALDH1A1 (0.88) L3MBTL1ALDH1A1HTTGAATP53
SCHEMBL13346213 0.86 ALDH1A1 (0.88) L3MBTL1ALDH1A1HTTGAATP53
SCHEMBL2622416 0.86 ALDH1A1 (0.88) L3MBTL1ALDH1A1HTTGAATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0274128-B1 Liquid-crystalline polymer IDEMITSU KOSAN CO (JP) 1999-03-31 EP disclosed
US-4877858-A FERROELECTRICAL HIG SPEED RESPONSE; DISPLAYS IDEMETSU KOSAN CO., LTD. (JP) 1989-10-31 US disclosed
EP-0274128-A2 Liquid-crystalline polymer IDEMITSU KOSAN COMPANY LIMITED (JP) 1988-07-13 EP disclosed