Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 8/20 | 0.52 |
| ▸ | ITGA2B | P08514 | 8/20 | 0.52 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7284564 | 1.00 | ITGB3 (0.52) | ITGB3ITGA2BRORCSIGMAR1HRH3 | |
| SCHEMBL8379879 | 0.86 | ITGB3 (0.43) | ITGB3ITGA2BSIGMAR1HRH3SLC6A3 | |
| SCHEMBL8377684 | 0.84 | ITGB3 (0.72) | ITGB3ITGA2B | |
| SCHEMBL8379338 | 0.84 | ITGB3 (0.72) | ITGB3ITGA2B | |
| SCHEMBL8379353 | 0.84 | ITGB3 (0.72) | ITGB3ITGA2B | |
| SCHEMBL8379326 | 0.84 | ITGB3 (0.72) | ITGB3ITGA2B | |
| SCHEMBL8643891 | 0.84 | SIGMAR1 (0.45) | SIGMAR1SLC6A3POLB | |
| SCHEMBL8379068 | 0.84 | ITGB3 (0.57) | ITGB3ITGA2B | |
| SCHEMBL14427048 | 0.84 | ITGB3 (0.71) | ITGB3ITGA2B | |
| SCHEMBL8379793 | 0.84 | ITGB3 (0.57) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5973188-A | Acetic acid derivatives | HOFFMANN-LA ROCHE INC. (US) | 1999-10-26 | — | — | US | disclosed |