SCHEMBL8380109

SCHEMBL8380109

CCCCC(CCCCCl)C1OC1C

nearest known ligand 0.39

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.39
ALDH1A1 P00352 1/20 0.39
TDP1 Q9NUW8 1/20 0.37
DNM1 Q05193 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31315055 0.84 DNM1 (0.42) TSHRDNM1
SCHEMBL11505534 0.80 DNM1 (0.39) DNM1
SCHEMBL51032 0.74
SCHEMBL7113503 0.72 DNM1 (0.34) DNM1
SCHEMBL10987980 0.69 DNM1 (0.33) ALDH1A1TDP1DNM1
SCHEMBL18107310 0.68 TSHR (0.52) TSHRALDH1A1TDP1DNM1
SCHEMBL51028 0.67 OGA (0.40) ALDH1A1
SCHEMBL29173026 0.66 TSHR (0.57) TSHRALDH1A1TDP1DNM1
SCHEMBL21484038 0.66 TSHR (0.57) TSHRALDH1A1TDP1DNM1
SCHEMBL18184497 0.66 ALDH1A1 (0.52) TSHRALDH1A1TDP1DNM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015127276-A1 POLYOL COMPOSITIONS FOR HOT MELT ADHESIVES IFS Industries Inc. (US) 2015-08-27 WO disclosed
EP-0901481-A1 PURIFICATION OF GLYCIDYL ESTERS BY THIN FILM EVAPORATION EXXON CHEMICAL PATENTS INC. (US) 1999-03-17 EP disclosed
WO-1997044335-A1 PURIFICATION OF GLYCIDYL ESTERS BY THIN FILM EVAPORATION EXXON CHEMICAL PATENTS INC. (US) 1997-11-27 WO disclosed