Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 8/20 | 0.32 |
| ▸ | RXRA | P19793 | 6/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 6/20 | 0.32 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.32 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.32 |
| ▸ | DHODH | Q02127 | 2/20 | 0.31 |
| ▸ | PDE5A | O76074 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | USP7 | Q93009 | 1/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9312803 | 1.00 | ACACB (0.34) | ACACBNPY5RCYP11B1CYP11B2GRIN2B | |
| SCHEMBL8382535 | 0.91 | ACACB (0.35) | ACACBNPY5RCYP11B1CYP11B2GRIN2B | |
| SCHEMBL8382537 | 0.91 | ACACB (0.35) | ACACBNPY5RCYP11B1CYP11B2GRIN2B | |
| SCHEMBL9311907 | 0.91 | ACACB (0.35) | ACACBNPY5RCYP11B1CYP11B2GRIN2B | |
| SCHEMBL8383724 | 0.90 | CYP11B1 (0.36) | ACACBCYP11B1CYP11B2GRIN2BRXRA | |
| SCHEMBL9312474 | 0.90 | CHRNB1 (0.35) | CYP11B1CYP11B2GRIN2BGRIN1DHODH | |
| SCHEMBL8380287 | 0.90 | CHRNB1 (0.35) | CYP11B1CYP11B2GRIN2BGRIN1DHODH | |
| SCHEMBL9313556 | 0.90 | CYP11B1 (0.36) | ACACBCYP11B1CYP11B2GRIN2BRXRA | |
| SCHEMBL8380279 | 0.87 | KDM1A (0.40) | CYP11B1CYP11B2GRM2ALDH1A1CYP1A2 | |
| SCHEMBL9312015 | 0.87 | KDM1A (0.40) | CYP11B1CYP11B2GRM2ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0475273-B1 | Liquid crystal mixture containing halogenated alcenyl compounds | MERCK PATENT GMBH (DE) | 1999-04-07 | — | — | EP | disclosed |
| US-5292452-A | Electrooptical devices; high dielectric anisotropy, low rotation viscosity, short response time | HOFFMANN-LA ROCHE INC. (US) | 1994-03-08 | — | — | US | disclosed |
| EP-0475273-A1 | Halogenated alcenyl compounds | F. HOFFMANN-LA ROCHE AG (CH) | 1992-03-18 | — | — | EP | disclosed |