Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB1 | P11230 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | AXL | P30530 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.34 |
| ▸ | SLC9A1 | P19634 | 4/20 | 0.33 |
| ▸ | PLAT | P00750 | 2/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8380287 | 1.00 | CHRNB1 (0.35) | CHRNB1CHRNB2CHRNB4CHRNA3CHRNB3 | |
| SCHEMBL9313058 | 0.91 | CHRNB1 (0.34) | CHRNB1CHRNB2CHRNB4CHRNA3CHRNB3 | |
| SCHEMBL8381946 | 0.91 | CHRNB1 (0.34) | CHRNB1CHRNB2CHRNB4CHRNA3CHRNB3 | |
| SCHEMBL8381945 | 0.91 | CHRNB1 (0.34) | CHRNB1CHRNB2CHRNB4CHRNA3CHRNB3 | |
| SCHEMBL8383724 | 0.91 | CYP11B1 (0.36) | CYP11B1CYP11B2DHODHKCNH2GRIN2B | |
| SCHEMBL9313556 | 0.91 | CYP11B1 (0.36) | CYP11B1CYP11B2DHODHKCNH2GRIN2B | |
| SCHEMBL9312803 | 0.90 | ACACB (0.34) | CYP11B1CYP11B2GRM2DHODHGRIN2B | |
| SCHEMBL8380299 | 0.90 | ACACB (0.34) | CYP11B1CYP11B2GRM2DHODHGRIN2B | |
| SCHEMBL9312443 | 0.90 | S1PR3 (0.34) | CYP11B1CYP11B2S1PR1S1PR3GRIN2B | |
| SCHEMBL8381988 | 0.90 | S1PR3 (0.34) | CYP11B1CYP11B2S1PR1S1PR3GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5292452-A | Electrooptical devices; high dielectric anisotropy, low rotation viscosity, short response time | HOFFMANN-LA ROCHE INC. (US) | 1994-03-08 | — | — | US | disclosed |