SCHEMBL8380353

SCHEMBL8380353

COC(CC1=CCc2ccccc21)CC1=CCc2ccccc21

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 1/20 0.45
KDM4E B2RXH2 1/20 0.31
MAP2K7 O14733 1/20 0.31
GMNN O75496 1/20 0.31
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31
TP53 P04637 1/20 0.31
CYP1A2 P05177 1/20 0.31
POLB P06746 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2D6 P10635 1/20 0.31
MAPT P10636 1/20 0.31
CYP2C9 P11712 1/20 0.31
HPGD P15428 1/20 0.31
ALOX15 P16050 1/20 0.31
CDC25A P30304 1/20 0.31
CDC25B P30305 1/20 0.31
CYP2C19 P33261 1/20 0.31
THPO P40225 1/20 0.31
MTOR P42345 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25453849 0.75 HTR6 (0.44) HTR6TP53
SCHEMBL30307384 0.75 HTR6 (0.44) HTR6ALDH1A1
SCHEMBL20996644 0.75 HTR6 (0.44) HTR6ALDH1A1
SCHEMBL23073839 0.75 HTR6 (0.44) HTR6
SCHEMBL14189738 0.74 HTR6 (0.41) HTR6ALDH1A1RAB9ASMN1; SMN2
SCHEMBL15114726 0.74 HTR6 (0.46) HTR6KDM4EMAP2K7CYP2D6CYP2C9
SCHEMBL6552816 0.74 HTR6 (0.53) HTR6KDM4ETP53RAB9A
SCHEMBL31121639 0.73 HTR6 (0.56) HTR6
SCHEMBL7618202 0.73 HTR6 (0.67) HTR6LMNATP53CYP1A2CYP3A4
SCHEMBL2338975 0.73 HTR6 (0.56) HTR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5977270-A Process using a rare earth metal catalyst for olefin polymerization UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1999-11-02 US disclosed
US-5744415-A Rare earth metal catalyst for olefin polymerization UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1998-04-28 US disclosed