SCHEMBL6552816

SCHEMBL6552816

CCC1=CCc2ccccc21

nearest known ligand 0.59

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 1/20 0.53
MPO P05164 1/20 0.40
ACHE P22303 1/20 0.35
HTR7 P34969 1/20 0.34
NPSR1 Q6W5P4 1/20 0.33
KDM4E B2RXH2 1/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
KMT2A Q03164 1/20 0.33
CES1 P23141 1/20 0.32
MAOA P21397 1/20 0.32
TP53 P04637 1/20 0.32
MTNR1A P48039 1/20 0.32
MTNR1B P49286 1/20 0.32
CYP19A1 P11511 1/20 0.32
CYP11B1 P15538 1/20 0.32
CYP11B2 P19099 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14154630 0.84 CES1 (0.45) HTR6ACHENPSR1KDM4ENPC1
SCHEMBL5859128 0.83 HTR6 (0.50) HTR6HTR7NPSR1KMT2AMTNR1A
SCHEMBL2338975 0.82 HTR6 (0.56) HTR6ACHEHTR7CES1MAOA
SCHEMBL7618202 0.82 HTR6 (0.67) HTR6HTR7NPSR1NPC1RAB9A
SCHEMBL31121639 0.82 HTR6 (0.56) HTR6ACHEHTR7CES1MAOA
SCHEMBL6666864 0.81 HTR6 (0.45) HTR6HTR7NPC1RAB9AMAOA
SCHEMBL20430497 0.80 HTR6 (0.47) HTR6HTR7
SCHEMBL6683869 0.80 HTR6 (0.47) HTR6HTR7MTNR1AMTNR1B
SCHEMBL29663816 0.80 HTR6 (0.47) HTR6HTR7
SCHEMBL20219247 0.79 HTR6 (0.50) HTR6HTR7CES1MAOAMTNR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 157 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109071685-B Terminal-modified conjugated diene polymer, rubber composition, and rubber article 株式会社普利司通 2020-12-01 CN claimed
US-12441901-B2 Quantum dot ink composition, and quantum dot electroluminescent device SAMSUNG ELECTRONICS CO., LTD. (KR) 2025-10-14 US disclosed
EP-3105261-B9 PRODUCING POLYETHYLENE PRODUCTS WITH IMPROVED STIFFNESS, TOUGHNESS, AND PROCESSABILITY UNIVATION TECH LLC (US) 2024-10-30 EP disclosed
CN-118164913-A Indenopiperidine derivatives, and preparation method and application thereof 浙江大学 2024-06-11 CN disclosed
EP-3663323-B1 PRODUCING POLYOLEFIN PRODUCTS UNIVATION TECH LLC (US) 2024-03-20 EP disclosed
US-20240076427-A1 PRODUCING POLYOLEFIN PRODUCTS UNIVATION TECHNOLOGIES, LLC (US) 2024-03-07 US disclosed
CN-114805656-B Production of polyolefin products 尤尼威蒂恩技术有限责任公司 2024-02-27 CN disclosed
EP-3680265-B1 METHOD FOR PRODUCING COPOLYMER, COPOLYMER, RUBBER COMPOSITION, AND TIRE BRIDGESTONE CORP (JP) 2024-01-17 EP disclosed
US-20230287231-A1 QUANTUM DOT INK COMPOSITION, AND QUANTUM DOT ELECTROLUMINESCENT DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-09-14 US disclosed
EP-3105264-B1 PRODUCING POLYOLEFIN PRODUCTS UNIVATION TECH LLC (US) 2023-09-06 EP disclosed
WO-2015123179-A1 PRODUCING POLYOLEFIN PRODUCTS UNIVATION TECHNOLOGIES, LLC (US) 2015-08-20 WO disclosed
US-8383848-B2 Transition metal compound and catalyst for olefin polymerization SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-02-26 US disclosed
US-20110319578-A1 TRANSITION METAL COMPOUND AND CATALYST FOR OLEFIN POLYMERIZATION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-12-29 US disclosed
EP-0834515-B1 New Organotransition Metal Compounds KANTO KAGAKU (JP) 2004-02-25 EP disclosed
CN-1478105-A A method for preparing catalyst composition and its use in polymerization process 尤尼威蒂恩技术有限责任公司 2004-02-25 CN disclosed
EP-0834514-B1 Process for synthesizing metallocene compounds KANTO KAGAKU (JP) 2003-10-22 EP disclosed
CN-1098869-C Process for preparing elastomeric EP(D)M copolymers ENICHEM SPA (IT) 2003-01-15 CN disclosed
US-5859276-A Organotransition metal compounds KANTO KAGAKU KABUSHIKI KAISHA (JP) 1999-01-12 US disclosed
CN-1172816-A Process for preparing elastomeric EP(D)M copolymers ENICHEM SPA (IT) 1998-02-11 CN disclosed
US-4137419-A FROM AN INDENE OR DIHYDRONAPHTHALENE GULF RESEARCH & DEVELOPMENT COMPANY (US) 1979-01-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110319578-A1 TRANSITION METAL COMPOUND AND CATALYST FOR OLEFIN POLYMERIZATION AP1M1, SOD1, YAP1 HTR6 4382/4885MPO 32/4885ACHE 1482/4885
US-20240076427-A1 PRODUCING POLYOLEFIN PRODUCTS DNMT1, DNMT3B, DNMT3L HTR6 2518/4885MPO 1925/4885ACHE 2913/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.