SCHEMBL8380594

SCHEMBL8380594

C1=CC(C(CC=[Hf]2CC2)C2C=Cc3ccccc32)c2ccccc21

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 1/20 0.32
HTR2A P28223 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8384531 0.79 HTR2A (0.36) HTR6HTR2A
SCHEMBL8382873 0.78 HTR2A (0.35) HTR6HTR2A
SCHEMBL8384031 0.78 HTR2A (0.35) HTR6HTR2A
SCHEMBL8384387 0.76 HTR6 (0.32) HTR6HTR2A
SCHEMBL8380394 0.76 HTR6 (0.32) HTR6HTR2A
SCHEMBL3383301 0.75 HTR2A (0.38) HTR6HTR2A
SCHEMBL8380397 0.73 HTR6 (0.32) HTR6HTR2A
SCHEMBL1921591 0.72 HTR2A (0.38) HTR6HTR2A
SCHEMBL3383305 0.72 HTR2A (0.38) HTR6HTR2A
SCHEMBL8384388 0.72 HTR6 (0.31) HTR6HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5916982-A Process for the production of polyolefins NIPPON OIL CO., LTD. (JP) 1999-06-29 US disclosed
EP-0768320-A1 Catalyst component and catalyst NIPPON OIL CO. LTD. (JP) 1997-04-16 EP disclosed
EP-0768319-A1 Process for the production of polyolefins NIPPON OIL CO. LTD. (JP) 1997-04-16 EP disclosed