Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9860034 | 0.98 | HTR2A (0.37) | HTR2AHTR6SIGMAR1KDM4ELMNA | |
| SCHEMBL6673086 | 0.85 | HTR2A (0.36) | HTR2AHTR6SIGMAR1KDM4ELMNA | |
| SCHEMBL30084485 | 0.83 | SIGMAR1 (0.38) | HTR2AHTR6SIGMAR1KDM4ELMNA | |
| SCHEMBL5034593 | 0.83 | SIGMAR1 (0.38) | HTR2AHTR6SIGMAR1KDM4ELMNA | |
| SCHEMBL6675368 | 0.82 | HTR2A (0.35) | HTR2AHTR6SIGMAR1KDM4ELMNA | |
| Hydrochloric Acid SCHEMBL4476663 | 0.82 | HTR6 (0.32) | HTR2AHTR6SIGMAR1TACR1 | |
| SCHEMBL6055362 | 0.81 | HTR2A (0.36) | HTR2AHTR6SIGMAR1KDM4ELMNA | |
| SCHEMBL4466071 | 0.81 | HTR2A (0.36) | HTR2AHTR6SIGMAR1KDM4ELMNA | |
| SCHEMBL11623231 | 0.81 | HTR2A (0.36) | HTR2AHTR6SIGMAR1KDM4ELMNA | |
| SCHEMBL30530453 | 0.81 | HTR2A (0.36) | HTR2AHTR6SIGMAR1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670681-A | Process for preparing a carbon-bridged biscyclopentadiene compound | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-09-23 | — | — | US | claimed |
| EP-0462588-A2 | Olefin block copolymer and method of producing same | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1991-12-27 | — | — | EP | claimed |
| EP-2328906-A1 | PREPARATION OF ANSA METALLOCENE COMPOUNDS | Basell Polyolefine GmbH (DE) | 2011-06-08 | — | — | EP | disclosed |
| WO-2010022878-A1 | PREPARATION OF ANSA METALLOCENE COMPOUNDS | BASELL POLYOLEFINE GMBH (DE) | 2010-03-04 | — | — | WO | disclosed |
| EP-1500659-B1 | Selective, catalytic, thermal functionalization of secondary or aromatic C-H bonds in cyclic hydrocarbons | SHELL INT RESEARCH (NL) | 2008-09-24 | — | — | EP | disclosed |
| EP-1268490-B1 | SELECTIVE, CATALYTIC, THERMAL FUNCTIONALIZATION OF SECONDARY OR AROMATIC C-H BONDS IN CYCLIC HYDROCARBONS | SHELL INT RESEARCH (NL) | 2005-01-26 | — | — | EP | disclosed |
| EP-1500659-A1 | Selective, catalytic, thermal functionalization of secondary or aromatic C-H bonds in cyclic hydrocarbons | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 2005-01-26 | — | — | EP | disclosed |
| EP-0963990-B1 | PROCESS FOR PRODUCING CYCLOPENTADIENYL METAL SALTS AND PROCESS FOR PRODUCING CYCLOPENTADIENE DERIVATIVES BY UTILIZING THE SAME | SUMITOMO CHEMICAL CO (JP) | 2004-10-06 | — | — | EP | disclosed |
| EP-0969010-B1 | Transition metal compound and catalyst containing the same for polymerization of olefins | JAPAN POLYOLEFINS CO LTD (JP) | 2004-09-22 | — | — | EP | disclosed |
| EP-0694563-B1 | Olefin polymerization catalyst and process for preparing polyolefins | NIPPON MITSUBISHI OIL CORP (JP) | 2002-10-30 | — | — | EP | disclosed |
| US-6451937-B1 | BY THERMALLY REACTING A FUNCTIONALIZING REAGENT AND THE HYDROCARBON IN THE PRESENCE OF A TRANSITION METAL COORDINATION CATALYST | SHELL OIL COMPANY | 2002-09-17 | — | — | US | disclosed |
| EP-0714920-A1 | Catalyst for polymerization of olefins | NIPPON OIL CO. LTD. (JP) | 1996-06-05 | — | — | EP | disclosed |
| EP-0694563-A1 | Olefin polymerization catalyst and process for preparing polyolefins | NIPPON OIL COMPANY, LIMITED (JP) | 1996-01-31 | — | — | EP | disclosed |
| EP-0679662-A1 | Catalyst component for the polymerization of olefins | NIPPON OIL CO. LTD. (JP) | 1995-11-02 | — | — | EP | disclosed |
| EP-0669346-A1 | Solid catalyst components for olefin polymerization and use thereof | NIPPON OIL CO. LTD. (JP) | 1995-08-30 | — | — | EP | disclosed |
| EP-0587440-A2 | Catalyst component for the polymerisation of olefins and process for preparing olefin polymers using same | NIPPON OIL COMPANY, LIMITED (JP) | 1994-03-16 | — | — | EP | disclosed |
| EP-0365974-B1 | Process for preparing an ethylene-propylene copolymer | HOECHST AG (DE) | 1993-12-29 | — | — | EP | disclosed |
| EP-0569249-A2 | Ethylene/alpha-olefin copolymers | NIPPON OIL COMPANY, LIMITED (JP) | 1993-11-10 | — | — | EP | disclosed |
| EP-0462588-A2 | Olefin block copolymer and method of producing same | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1991-12-27 | — | — | EP | disclosed |
| EP-0365974-A2 | Process for preparing an ethylene-propylene copolymer | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-05-02 | — | — | EP | disclosed |