Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | RARA | P10276 | 1/20 | 0.44 |
| ▸ | RARG | P13631 | 1/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.43 |
| ▸ | KDM1A | O60341 | 6/20 | 0.41 |
| ▸ | GPR3 | P46089 | 1/20 | 0.41 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.40 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4818894 | 0.99 | RARB (0.45) | RARBTSHRHSD17B10RARARARG | |
| SCHEMBL8377160 | 0.99 | RARB (0.45) | RARBTSHRHSD17B10RARARARG | |
| SCHEMBL8379621 | 0.91 | CYP11B1 (0.47) | CYP11B1CYP11B2KDM1AKCNJ1 | |
| SCHEMBL4820484 | 0.91 | CYP11B1 (0.47) | CYP11B1CYP11B2KDM1AKCNJ1 | |
| SCHEMBL9755559 | 0.89 | TSHR (0.49) | RARBTSHRHSD17B10RARARARG | |
| SCHEMBL8377978 | 0.85 | RARB (0.44) | RARBTSHRHSD17B10RARARARG | |
| SCHEMBL11572123 | 0.83 | TSHR (0.65) | RARBTSHRHSD17B10KDM1AGPR3 | |
| SCHEMBL9632643 | 0.83 | TSHR (0.65) | RARBTSHRHSD17B10KDM1AGPR3 | |
| SCHEMBL4603532 | 0.83 | TSHR (0.65) | RARBTSHRHSD17B10KDM1AGPR3 | |
| SCHEMBL4605460 | 0.83 | TSHR (0.65) | RARBTSHRHSD17B10KDM1AGPR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5958290-A | ELECTROOPTICAL APPARATUS WITH DIELECTRIC LIQUID CRYSTALS FOR RADIATION TRANSPARENT MEDIUM | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1999-09-28 | — | — | US | disclosed |
| US-5344587-A | Nitriles | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1994-09-06 | — | — | US | disclosed |
| WO-1991005029-A1 | ELECTRO-OPTICAL LIQUID CRYSTAL SYSTEM | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1991-04-18 | — | — | WO | disclosed |