SCHEMBL8380773

SCHEMBL8380773

C[Si](C)(C)N1CCCCCCCC1

nearest known ligand 0.41

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL918211 1.00 MGLL (0.30) MGLL
SCHEMBL11793916 0.97
SCHEMBL378577 0.96
SCHEMBL11792286 0.89
SCHEMBL8077052 0.87
SCHEMBL11799504 0.86
SCHEMBL11789995 0.81
SCHEMBL9980594 0.81
SCHEMBL8832416 0.79 MGLL (0.30) MGLL
SCHEMBL29016463 0.79 MGLL (0.30) MGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0694559-B1 2',5'-Phosphorothioate oligoadenylates and antiviral uses thereof UNIV TEMPLE (US) 1999-04-14 EP disclosed
US-5556840-A 2',5'-phosphorothioate oligoadenylates as anitiviral agents TEMPLE UNIVERSITY - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) 1996-09-17 US disclosed
EP-0389521-B1 2',5'-PHOSPHOROTHIOATE OLIGOADENYLATES AND ANTIVIRAL USES THEREOF UNIV TEMPLE (US) 1996-03-20 EP disclosed
EP-0694559-A2 2',5'-Phosphorothioate oligoadenylates and antiviral uses thereof Temple University of the Commonwealth System of Higher Education (US) 1996-01-31 EP disclosed
US-5405939-A viricides TEMPLE UNIVERSITY OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) 1995-04-11 US disclosed
US-5188897-A Viricides, metabolic stability TEMPLE UNIVERSITY OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) 1993-02-23 US disclosed
EP-0389521-A4 2',5'-PHOSPHOROTHIOATE OLIGOADENYLATES AND ANTIVIRAL USES THEREOF 1992-02-05 EP disclosed
EP-0389521-A1 2',5'-PHOSPHOROTHIOATE OLIGOADENYLATES AND ANTIVIRAL USES THEREOF Temple University of the Commonwealth System of Higher Education (US) 1990-10-03 EP disclosed
US-4924624-A TOBACCO MOSAIC VIRUS TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) 1990-05-15 US disclosed
WO-1989003683-A1 2',5'-PHOSPHOROTHIOATE OLIGOADENYLATES AND ANTIVIRAL USES THEREOF TEMPLE UNIVERSITY OF THE COMMONWEALTH SYSTEM OF HI (US) 1989-05-05 WO disclosed