SCHEMBL8380814

SCHEMBL8380814

[SiH3][SiH2][SiH](c1ccccc1)c1ccccc1

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.32
HPGD P15428 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
MGLL Q99685 1/20 0.32
HSD17B10 Q99714 1/20 0.32
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8380409 0.72 TSHR (0.32)
SCHEMBL9813480 0.72 DAO (0.32)
SCHEMBL826572 0.72 DAO (0.32)
SCHEMBL2903329 0.71 TSHR (0.35) MAPTHPGDSMN1; SMN2MGLLHSD17B10
SCHEMBL8384810 0.71 LMNA (0.33) MAPTHPGDSMN1; SMN2MGLLHSD17B10
SCHEMBL8383799 0.69 MAPT (0.30) MAPTHPGDSMN1; SMN2MGLLHSD17B10
SCHEMBL8380391 0.67 TP53 (0.33)
SCHEMBL8381512 0.67 MAPK1 (0.30)
SCHEMBL8383978 0.65 TP53 (0.36) MAPTHPGDSMN1; SMN2MGLLHSD17B10
SCHEMBL8380376 0.65 MAPK1 (0.32) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3167459-A1 POLYMERIC FEED-THRU FOR CHRONIC IMPLANTABLE DEVICES Cardiac Pacemakers, Inc. (US) 2017-05-17 EP disclosed
WO-2016007367-A1 POLYMERIC FEED-THRU FOR CHRONIC IMPLANTABLE DEVICES CARDIAC PACEMAKERS, INC. (US) 2016-01-14 WO disclosed
EP-0630933-B1 A method of producing a semiconducting material NIPPON OIL CO LTD (JP) 1999-04-14 EP disclosed
US-5700400-A Method for producing a semiconducting material NIPPON OIL CO., LTD. (JP) 1997-12-23 US disclosed
EP-0551771-B1 Process for producing polysilanes NIPPON OIL CO LTD (JP) 1997-07-30 EP disclosed
US-5620531-A Photovoltaic element NIPPON OIL CO., LTD. (JP) 1997-04-15 US disclosed
EP-0717451-A2 Photovoltaic element NIPPON OIL CO., LTD. (JP) 1996-06-19 EP disclosed
EP-0630933-A2 A method of producing a semiconducting material NIPPON OIL CO. LTD. (JP) 1994-12-28 EP disclosed
US-5304622-A Process for producing polysilanes NIPPON OIL COMPANY, LTD. (JP) 1994-04-19 US disclosed
EP-0551771-A2 Process for producing polysilanes NIPPON OIL CO. LTD. (JP) 1993-07-21 EP disclosed