SCHEMBL8380376

SCHEMBL8380376

CC(C)(C)[SiH2][SiH](c1ccccc1)c1ccccc1

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.32
TAAR1 Q96RJ0 2/20 0.30
ALDH1A1 P00352 1/20 0.30
ALOX15 P16050 1/20 0.30
SLC6A2 P23975 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8385111 0.76 MAPK1 (0.30) MAPK1
SCHEMBL8384810 0.70 LMNA (0.33) ALDH1A1
SCHEMBL18398 0.65 MAPK1 (0.36) MAPK1TAAR1ALDH1A1ALOX15SLC6A2
SCHEMBL8381893 0.65 ALDH1A1 (0.37) MAPK1TAAR1ALDH1A1ALOX15SLC6A2
SCHEMBL2903329 0.65 TSHR (0.35) ALDH1A1
SCHEMBL8380814 0.65 MAPT (0.32) ALDH1A1
SCHEMBL3691011 0.65 MAPK1 (0.36) MAPK1TAAR1ALDH1A1ALOX15SLC6A2
SCHEMBL27704625 0.65 MAPK1 (0.32) MAPK1TAAR1ALDH1A1ALOX15SLC6A2
SCHEMBL8383978 0.65 TP53 (0.36) TAAR1SLC6A2
Hydrochloric Acid SCHEMBL1295227 0.63 MAPK1 (0.35) MAPK1TAAR1ALDH1A1ALOX15SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015032357-A1 ZANAMIVIR, ZANAMIVIR INTERMEDIATE, AND SYNTHESIS METHOD 中国科学院上海有机化学研究所 (CN) 2015-03-12 WO disclosed
EP-0630933-B1 A method of producing a semiconducting material NIPPON OIL CO LTD (JP) 1999-04-14 EP disclosed
US-5700400-A Method for producing a semiconducting material NIPPON OIL CO., LTD. (JP) 1997-12-23 US disclosed
EP-0551771-B1 Process for producing polysilanes NIPPON OIL CO LTD (JP) 1997-07-30 EP disclosed
US-5620531-A Photovoltaic element NIPPON OIL CO., LTD. (JP) 1997-04-15 US disclosed
EP-0717451-A2 Photovoltaic element NIPPON OIL CO., LTD. (JP) 1996-06-19 EP disclosed
EP-0630933-A2 A method of producing a semiconducting material NIPPON OIL CO. LTD. (JP) 1994-12-28 EP disclosed
US-5304622-A Process for producing polysilanes NIPPON OIL COMPANY, LTD. (JP) 1994-04-19 US disclosed
EP-0551771-A2 Process for producing polysilanes NIPPON OIL CO. LTD. (JP) 1993-07-21 EP disclosed