Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8380240 | 0.83 | GAA (0.50) | CYP2C19NPC1GAAMAPTCYP2C9 | |
| SCHEMBL8383503 | 0.83 | MAPT (0.49) | CYP2C19NPC1ALDH1A1CYP2D6GAA | |
| SCHEMBL7627658 | 0.78 | MAPT (0.50) | NPC1GAAMAPTMEN1TP53 | |
| SCHEMBL7630025 | 0.75 | HDAC1 (0.45) | CYP2C19ALDH1A1GAAMAPTCYP2C9 | |
| SCHEMBL18235820 | 0.74 | GAA (0.59) | NPC1GAAMAPTMEN1HPGD | |
| SCHEMBL7634000 | 0.73 | TSHR (0.44) | CYP2C19ALDH1A1GAAMAPTCYP2C9 | |
| SCHEMBL9460074 | 0.73 | LTA4H (0.57) | GAAMAPTCSNK2A1MEN1TP53 | |
| SCHEMBL8383297 | 0.73 | ADRB3 (0.48) | ALDH1A1GAAMAPTMEN1HPGD | |
| SCHEMBL8384881 | 0.72 | GAA (0.46) | GAAMAPTCSNK2A1MEN1TSHR | |
| SCHEMBL8382530 | 0.70 | MAPT (0.55) | NPC1ALDH1A1GAAMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5972949-A | COMPOUNDS SUCH AS 4-(1-PYRAZOLYL)METHYLPHENYL 2-(2-PYRIMIDYLOXY) ETHYL ETHER; INSECTICIDAL AND/OR ACARICIDAL AGENTS | SUMITO CHEMICAL CO., LTD. (JP) | 1999-10-26 | — | — | US | disclosed |
| US-5883262-A | INSECTICIDES, ACARICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-03-16 | — | — | US | disclosed |
| EP-0757048-A1 | ETHER COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1997-02-05 | — | — | EP | disclosed |