Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 6/20 | 0.51 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.42 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29792804 | 0.97 | TYMP (0.50) | TYMPPRMT6ADORA1P2RY12ADORA2A | |
| SCHEMBL18797899 | 0.95 | PRMT6 (0.52) | TYMPPRMT6ADORA1P2RY12ADORA2A | |
| SCHEMBL18797898 | 0.95 | PRMT6 (0.52) | TYMPPRMT6ADORA1P2RY12ADORA2A | |
| SCHEMBL8385935 | 0.94 | TYMP (0.55) | TYMPADORA1P2RY12ADORA2AADORA2B | |
| SCHEMBL20482910 | 0.94 | TYMP (0.55) | TYMPADORA1P2RY12ADORA2AADORA2B | |
| SCHEMBL19493438 | 0.94 | TYMP (0.55) | TYMPPRMT6ADORA1P2RY12ADORA2A | |
| SCHEMBL21591934 | 0.94 | TYMP (0.55) | TYMPADORA1P2RY12ADORA2AADORA2B | |
| SCHEMBL21305068 | 0.94 | TYMP (0.55) | TYMPPRMT6ADORA1P2RY12ADORA2A | |
| SCHEMBL6396836 | 0.94 | TYMP (0.55) | TYMPPRMT6ADORA1P2RY12ADORA2A | |
| SCHEMBL8385934 | 0.94 | TYMP (0.55) | TYMPADORA1P2RY12ADORA2AADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0694559-B1 | 2',5'-Phosphorothioate oligoadenylates and antiviral uses thereof | UNIV TEMPLE (US) | 1999-04-14 | — | — | EP | disclosed |
| US-5556840-A | 2',5'-phosphorothioate oligoadenylates as anitiviral agents | TEMPLE UNIVERSITY - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 1996-09-17 | — | — | US | disclosed |
| EP-0389521-B1 | 2',5'-PHOSPHOROTHIOATE OLIGOADENYLATES AND ANTIVIRAL USES THEREOF | UNIV TEMPLE (US) | 1996-03-20 | — | — | EP | disclosed |
| EP-0694559-A2 | 2',5'-Phosphorothioate oligoadenylates and antiviral uses thereof | Temple University of the Commonwealth System of Higher Education (US) | 1996-01-31 | — | — | EP | disclosed |
| US-5405939-A | viricides | TEMPLE UNIVERSITY OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 1995-04-11 | — | — | US | disclosed |
| US-5188897-A | Viricides, metabolic stability | TEMPLE UNIVERSITY OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 1993-02-23 | — | — | US | disclosed |
| EP-0389521-A4 | 2',5'-PHOSPHOROTHIOATE OLIGOADENYLATES AND ANTIVIRAL USES THEREOF | — | 1992-02-05 | — | — | EP | disclosed |
| EP-0389521-A1 | 2',5'-PHOSPHOROTHIOATE OLIGOADENYLATES AND ANTIVIRAL USES THEREOF | Temple University of the Commonwealth System of Higher Education (US) | 1990-10-03 | — | — | EP | disclosed |
| US-4924624-A | TOBACCO MOSAIC VIRUS | TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 1990-05-15 | — | — | US | disclosed |
| WO-1989003683-A1 | 2',5'-PHOSPHOROTHIOATE OLIGOADENYLATES AND ANTIVIRAL USES THEREOF | TEMPLE UNIVERSITY OF THE COMMONWEALTH SYSTEM OF HI (US) | 1989-05-05 | — | — | WO | disclosed |