Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 9/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.40 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8375653 | 0.85 | GRIA4 (0.42) | HSD17B10PPARGPDK2 | |
| SCHEMBL8376669 | 0.84 | TSHR (0.49) | KDM1ATSHRHSD17B10CYP11B2HRH3 | |
| SCHEMBL17108410 | 0.82 | TSHR (0.51) | KDM1ATSHRHSD17B10HRH3CYP2A6 | |
| SCHEMBL8375601 | 0.82 | NPC1 (0.45) | TSHRPDK2 | |
| SCHEMBL29306100 | 0.80 | TSHR (0.46) | KDM1ATSHRHSD17B10CYP11B2HRH3 | |
| SCHEMBL9228216 | 0.80 | GRIA4 (0.42) | TSHRCYP11B1CYP11B2LTB4R2PDK2 | |
| SCHEMBL9406878 | 0.79 | TSHR (0.54) | KDM1ATSHRHSD17B10HRH3CYP2A6 | |
| SCHEMBL29637013 | 0.79 | TSHR (0.54) | KDM1ATSHRHSD17B10HRH3CYP2A6 | |
| SCHEMBL7913848 | 0.79 | TSHR (0.54) | KDM1ATSHRHSD17B10HRH3CYP2A6 | |
| SCHEMBL13561685 | 0.78 | TSHR (0.55) | KDM1ATSHRHSD17B10CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5958290-A | ELECTROOPTICAL APPARATUS WITH DIELECTRIC LIQUID CRYSTALS FOR RADIATION TRANSPARENT MEDIUM | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1999-09-28 | — | — | US | disclosed |
| EP-0452460-B1 | ELECTRO-OPTICAL LIQUID CRYSTAL SYSTEM | MERCK PATENT GMBH (DE) | 1995-01-18 | — | — | EP | disclosed |
| US-5344587-A | Nitriles | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1994-09-06 | — | — | US | disclosed |
| EP-0452460-A1 | ELECTRO-OPTICAL LIQUID CRYSTAL SYSTEM. | MERCK PATENT GMBH (DE) | 1991-10-23 | — | — | EP | disclosed |
| WO-1991005029-A1 | ELECTRO-OPTICAL LIQUID CRYSTAL SYSTEM | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1991-04-18 | — | — | WO | disclosed |