⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10920636 | 0.80 | — | — | |
| SCHEMBL27447537 | 0.77 | — | — | |
| SCHEMBL28068398 | 0.75 | GRM4 (0.31) | — | |
| SCHEMBL29190482 | 0.75 | CYP3A4 (0.39) | — | |
| SCHEMBL28609429 | 0.73 | — | — | |
| SCHEMBL27573294 | 0.72 | LMNA (0.37) | — | |
| SCHEMBL28913672 | 0.72 | — | — | |
| SCHEMBL31277644 | 0.72 | — | — | |
| SCHEMBL28609569 | 0.72 | — | — | |
| SCHEMBL9705477 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108350014-A | Aminoglycoside derivatives and their use in the treatment of genetic disorders | ELOXX制药有限公司 | 2018-07-31 | — | — | CN | claimed |
| CN-114957357-A | Aminoglycoside derivatives and their use in the treatment of genetic disorders | ELOXX制药有限公司 | 2022-08-30 | — | — | CN | disclosed |
| CN-108350014-B | Aminoglycoside derivatives and their use in the treatment of genetic disorders | ELOXX制药有限公司 | 2022-06-10 | — | — | CN | disclosed |
| CN-108350014-A | Aminoglycoside derivatives and their use in the treatment of genetic disorders | ELOXX制药有限公司 | 2018-07-31 | — | — | CN | disclosed |
| EP-0906588-A1 | PHOTODEFINABLE DIELECTRIC COMPOSITIONS | THE B.F. GOODRICH COMPANY (US) | 1999-04-07 | — | — | EP | disclosed |
| WO-1998020394-A1 | PHOTODEFINABLE DIELECTRIC COMPOSITIONS | THE B.F. GOODRICH COMPANY (US) | 1998-05-14 | — | — | WO | disclosed |