SCHEMBL27573294

SCHEMBL27573294

O=C(O)C1=CCC(Cl)(C(=O)c2ccccc2)C=C1

nearest known ligand 0.37

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.37
DAO P14920 1/20 0.35
TSHR P16473 1/20 0.35
NAPRT Q6XQN6 1/20 0.35
CES2 O00748 4/20 0.33
CES1 P23141 4/20 0.33
SRD5A2 P31213 1/20 0.32
ALDH1A1 P00352 2/20 0.31
TRPA1 O75762 1/20 0.31
MAPK1 P28482 1/20 0.31
GSK3B P49841 1/20 0.31
HIF1A Q16665 1/20 0.31
AKR1C3 P42330 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11545163 0.88 LMNA (0.36) LMNACES2CES1
SCHEMBL5073219 0.84 CES2 (0.42) TSHRCES2CES1SRD5A2ALDH1A1
SCHEMBL9249033 0.83 MEN1 (0.43) LMNACES2SRD5A2ALDH1A1MAPK1
SCHEMBL6940929 0.83 LMNA (0.38) LMNADAOTSHRNAPRTCES2
SCHEMBL9386897 0.82 LMNA (0.37) LMNASRD5A2ALDH1A1
SCHEMBL28485936 0.81 LMNA (0.41) LMNADAOTSHRNAPRTCES2
SCHEMBL28497940 0.78 CES2 (0.38) LMNATSHRCES2CES1ALDH1A1
SCHEMBL28854112 0.74 AKR1C3 (0.37) LMNAALDH1A1AKR1C3
SCHEMBL27981573 0.72 LMNA (0.40) LMNADAOTSHRNAPRTCES2
SCHEMBL156513 0.71 ALDH1A1 (0.42) LMNADAOTSHRNAPRTCES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100477340-C Composite bodies used as separators in electrochemical cells BASF AG (DE) 2009-04-08 CN disclosed
CN-1331843-A Composite bodies used as separators in electrochemical cells BASF AG (DE) 2002-01-16 CN disclosed