Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KDM5A | P29375 | 3/20 | 0.34 |
| ▸ | BCHE | P06276 | 4/20 | 0.34 |
| ▸ | ACHE | P22303 | 4/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | KDM4A | O75164 | 5/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 5/20 | 0.33 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.33 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.33 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8381759 | 0.98 | LMNA (0.42) | LMNAMEN1KMT2AKDM5ABCHE | |
| SCHEMBL8381205 | 0.94 | LMNA (0.37) | LMNAMEN1KMT2AGAATSHR | |
| SCHEMBL8384866 | 0.86 | MEN1 (0.39) | LMNAMEN1KMT2ACHRM2GAA | |
| SCHEMBL8383339 | 0.82 | LMNA (0.41) | LMNAMEN1KMT2AKDM5ABCHE | |
| SCHEMBL4699893 | 0.82 | TSHR (0.47) | LMNAKDM5AKDM4AKDM4CKDM7A | |
| SCHEMBL8386752 | 0.81 | EPHX2 (0.36) | KDM5ABCHEACHEGAAKDM4C | |
| SCHEMBL8381762 | 0.81 | LMNA (0.43) | LMNAMEN1KMT2AKDM5ABCHE | |
| SCHEMBL4700836 | 0.81 | EPHX2 (0.49) | LMNAKDM5AKDM4AKDM4CKDM7A | |
| SCHEMBL16526222 | 0.78 | KDM5A (0.44) | LMNAKDM5AACHEKDM4CEPHX2 | |
| SCHEMBL8383263 | 0.78 | CHRM1 (0.34) | KDM5ABCHEACHECHRM1KDM4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5861429-A | MITICIDES AND ANTHELMINTICS | SANKYO COMPANY, LIMITED (JP) | 1999-01-19 | — | — | US | disclosed |