Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM5A | P29375 | 3/20 | 0.35 |
| ▸ | BCHE | P06276 | 4/20 | 0.35 |
| ▸ | ACHE | P22303 | 4/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KDM4A | O75164 | 5/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 5/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.33 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.33 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8381762 | 0.98 | LMNA (0.43) | LMNAMEN1KMT2AKDM5ABCHE | |
| SCHEMBL8381207 | 0.94 | LMNA (0.38) | LMNAMEN1KMT2AGAAFAAH | |
| SCHEMBL8384869 | 0.88 | MEN1 (0.39) | LMNAMEN1KMT2ACHRM2GAA | |
| SCHEMBL4699893 | 0.84 | TSHR (0.47) | LMNAKDM5AKDM4AKDM4CKDM7A | |
| SCHEMBL25571626 | 0.83 | CHRNB2 (0.36) | LMNAMEN1KMT2AACHECHRM2 | |
| SCHEMBL4700836 | 0.82 | EPHX2 (0.49) | LMNAKDM5AKDM4AKDM4CKDM7A | |
| SCHEMBL8383336 | 0.82 | LMNA (0.40) | LMNAMEN1KMT2AKDM5ABCHE | |
| SCHEMBL8381759 | 0.81 | LMNA (0.42) | LMNAMEN1KMT2AKDM5ABCHE | |
| SCHEMBL8386754 | 0.81 | ALOX15 (0.40) | MEN1KMT2AKDM5ABCHEACHE | |
| SCHEMBL21235768 | 0.79 | HDAC6 (0.42) | LMNAMEN1KMT2ABCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5861429-A | MITICIDES AND ANTHELMINTICS | SANKYO COMPANY, LIMITED (JP) | 1999-01-19 | — | — | US | disclosed |