Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | CTSD | P07339 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.32 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.30 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.30 |
| ▸ | FPR3 | P25089 | 1/20 | 0.30 |
| ▸ | FPR2 | P25090 | 1/20 | 0.30 |
| ▸ | ASGR1 | P07306 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL336495 | 0.81 | HDAC6 (0.37) | HDAC6HDAC1HDAC2CTSDCTSL | |
| SCHEMBL6445026 | 0.81 | HDAC6 (0.37) | HDAC6HDAC1HDAC2CTSDCTSL | |
| SCHEMBL256557 | 0.81 | HDAC6 (0.37) | HDAC6HDAC1HDAC2CTSDCTSL | |
| SCHEMBL1689401 | 0.81 | HDAC6 (0.37) | HDAC6HDAC1HDAC2CTSDCTSL | |
| SCHEMBL8383402 | 0.80 | HDAC6 (0.38) | HDAC6HDAC1HDAC2HTR2CSLC6A4 | |
| SCHEMBL24106653 | 0.79 | HDAC6 (0.36) | HDAC6HDAC1HDAC2CTSDCTSL | |
| SCHEMBL3187773 | 0.79 | HDAC6 (0.36) | HDAC6HDAC1HDAC2CTSDCTSL | |
| Ammonia Solution, Strong SCHEMBL29062672 | 0.79 | HDAC6 (0.36) | HDAC6HDAC1HDAC2CTSDCTSL | |
| SCHEMBL1926409 | 0.79 | HDAC6 (0.36) | HDAC6HDAC1HDAC2CTSDCTSL | |
| SCHEMBL13451748 | 0.79 | HDAC6 (0.40) | HDAC6HDAC1HDAC2CTSDCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5861429-A | MITICIDES AND ANTHELMINTICS | SANKYO COMPANY, LIMITED (JP) | 1999-01-19 | — | — | US | disclosed |