Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 4/20 | 0.60 |
| ▸ | HRH1 | P35367 | 4/20 | 0.60 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.50 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.49 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.49 |
| ▸ | DRD3 | P35462 | 2/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | MC4R | P32245 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9857294 | 0.90 | HTR2A (0.53) | HTR2AHRH1MTNR1AMTNR1BSLC6A4 | |
| SCHEMBL9856505 | 0.90 | HTR2A (0.53) | HTR2AHRH1MTNR1AMTNR1BSLC6A4 | |
| SCHEMBL9857112 | 0.90 | HTR2A (0.53) | HTR2AHRH1MTNR1AMTNR1BSLC6A4 | |
| SCHEMBL9856731 | 0.89 | SLC6A4 (0.55) | HTR2AHRH1MTNR1AMTNR1BSLC6A4 | |
| SCHEMBL9856936 | 0.89 | SLC6A4 (0.55) | HTR2AHRH1MTNR1AMTNR1BSLC6A4 | |
| SCHEMBL11583482 | 0.88 | HTR2A (0.56) | HTR2AHRH1MTNR1AMTNR1BSLC6A4 | |
| SCHEMBL9856456 | 0.87 | HTR2A (0.50) | HTR2AHRH1MTNR1AMTNR1BSLC6A4 | |
| SCHEMBL9856612 | 0.86 | ALDH1A1 (0.61) | HTR2AHRH1SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL9856914 | 0.86 | HTR2A (0.49) | HTR2AHRH1SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL9857051 | 0.86 | ALDH1A1 (0.69) | HTR2AHRH1SLC6A4SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0703216-B1 | Amidinophenol derivatives as protease inhibitors | ONO PHARMACEUTICAL CO (JP) | 1999-04-07 | — | — | EP | claimed |
| WO-2021141165-A1 | AMINO ALCOHOL-BORON-BINOL COMPOSITE AND METHOD FOR PREPARING OPTICALLY ACTIVE AMINO ALCOHOL DERIVATIVE USING SAME | (주)분자와물질 | 2021-07-15 | — | — | WO | disclosed |