Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | HRH1 | P35367 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.48 |
| ▸ | CASR | P41180 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9857051 | 0.94 | ALDH1A1 (0.69) | ALDH1A1MEN1KMT2AHTR2AHRH1 | |
| SCHEMBL8384207 | 0.86 | HTR2A (0.60) | ALDH1A1MEN1KMT2AHTR2AHRH1 | |
| SCHEMBL9856467 | 0.86 | SLC6A4 (0.52) | ALDH1A1MEN1KMT2AHTR2AHRH1 | |
| SCHEMBL9856490 | 0.85 | CHRM2 (0.56) | ALDH1A1SLC6A4CASRSLC6A2CYP2D6 | |
| SCHEMBL631023 | 0.84 | ALDH1A1 (0.66) | ALDH1A1MEN1KMT2ALTA4HSLC6A4 | |
| SCHEMBL9857294 | 0.83 | HTR2A (0.53) | ALDH1A1MEN1KMT2AHTR2AHRH1 | |
| SCHEMBL9857112 | 0.83 | HTR2A (0.53) | MEN1KMT2AHTR2AHRH1SLC6A4 | |
| SCHEMBL9856505 | 0.83 | HTR2A (0.53) | ALDH1A1MEN1KMT2AHTR2AHRH1 | |
| SCHEMBL9856731 | 0.82 | SLC6A4 (0.55) | MEN1KMT2AHTR2AHRH1SLC6A4 | |
| SCHEMBL9856936 | 0.82 | SLC6A4 (0.55) | MEN1KMT2AHTR2AHRH1SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4996235-A | Selectively inhibiting the uptake of serotonin and norepinephrine | ELI LILLY AND COMPANY (US) | 1991-02-26 | — | — | US | disclosed |