SCHEMBL8384544

SCHEMBL8384544

O=Cc1ccc(OP(=O)(O)O)c2ccccc12

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRC P12931 7/20 0.64
INPPL1 O15357 7/20 0.46
INPP5A Q14642 4/20 0.46
AKT1 P31749 1/20 0.46
INPP5B P32019 2/20 0.43
KDM4E B2RXH2 2/20 0.42
ALDH1A1 P00352 2/20 0.42
HPGD P15428 2/20 0.42
USP2 O75604 1/20 0.42
PDE3A Q14432 1/20 0.42
HSD17B10 Q99714 1/20 0.42
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
NPC1 O15118 1/20 0.36
HSP90AA1 P07900 1/20 0.36
IDO1 P14902 1/20 0.36
RAB9A P51151 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
LMNA P02545 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4195515 0.80 SRC (0.51) SRCINPPL1INPP5AAKT1INPP5B
SCHEMBL3514846 0.78 SRC (1.00) SRCINPPL1INPP5AAKT1INPP5B
SCHEMBL8386747 0.77 INPPL1 (0.68) SRCINPPL1INPP5AAKT1INPP5B
SCHEMBL10438501 0.77 PLK1 (0.53) SRCINPPL1INPP5AAKT1INPP5B
SCHEMBL2541603 0.77 INPPL1 (0.50) SRCINPPL1INPP5AAKT1INPP5B
SCHEMBL4198349 0.76 SRC (0.55) SRCINPPL1INPP5AAKT1INPP5B
SCHEMBL4804590 0.75 LMNA (0.38) SRCKDM4EALDH1A1HPGDMEN1
SCHEMBL2547022 0.75 IDO1 (0.53) SRCINPPL1INPP5AAKT1INPP5B
SCHEMBL545661 0.74 MAPT (0.54) KDM4EALDH1A1HPGDMEN1KMT2A
SCHEMBL29708066 0.74 MAPT (0.54) KDM4EALDH1A1HPGDMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0487343-B1 Process for preparing a lithographic plate FUJI PHOTO FILM CO LTD (JP) 1999-04-28 EP disclosed
EP-0487343-A1 Process for preparing a lithographic plate Fuji Photo Film Co., Ltd. (JP) 1992-05-27 EP disclosed