Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | MLYCD | O95822 | 5/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.36 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.36 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.36 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.34 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.34 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8385239 | 0.83 | CYP1A2 (0.41) | PDK1PDK2PDK3PDK4POLB | |
| SCHEMBL8386235 | 0.81 | SLC16A3 (0.44) | FFAR1FFAR4PDK1PDK2PDK3 | |
| SCHEMBL8485610 | 0.78 | PDK1 (0.38) | MLYCDPDK1PDK2PDK3PDK4 | |
| SCHEMBL8384024 | 0.72 | PDK1 (0.37) | FFAR1FFAR4MLYCDGAAPDK1 | |
| SCHEMBL12758952 | 0.71 | PDK1 (0.44) | GAAPDK1PDK2PDK3PDK4 | |
| SCHEMBL20981671 | 0.71 | MEN1 (0.54) | PDK1PDK2PDK3PDK4POLB | |
| SCHEMBL1173659 | 0.70 | KDM4E (0.45) | GAAPDK1PDK2PDK3PDK4 | |
| SCHEMBL12869586 | 0.70 | KDM4E (0.45) | GAAPDK1PDK2PDK3PDK4 | |
| SCHEMBL21630195 | 0.69 | KDM4E (0.44) | GAAPDK1PDK2PDK3PDK4 | |
| SCHEMBL12819705 | 0.69 | MAPT (0.50) | GAAPDK1PDK2PDK3PDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5932743-A | Methods for the solid phase synthesis of substituted indole compounds | AMERICAN HOME PRODUCTS CORPORATION (US) | 1999-08-03 | — | — | US | disclosed |
| WO-1999009007-A1 | SOLID PHASE SYNTHESIS OF 2,3-DISUBSTITUTED INDOLE COMPOUNDS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1999-02-25 | — | — | WO | disclosed |